Impact of Zinc and Vitamin D3 Supplementation on the Survival of Aged Patients Infected With COVID-19
NCT ID: NCT04351490
Last Updated: 2021-03-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
INTERVENTIONAL
2020-04-30
2020-07-31
Brief Summary
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Aged subjects are particularly prone to zinc and vitamin D deficiency. These two micronutrients are able to modulate the immune response by reducing the inflammatory storm.
The hypothesis is that supplementation with zinc and vitamin D would reduce the inflammatory reaction which worsens ARDS and leads to the death of subjects infected with Covid-19.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Group supplementation
Zinc gluconate
Zinc gluconate capsule 15 mg x 2 per day during 2 months
25-OH cholecalciferol
25-OH cholecalciferol drinkable solution 10 drops (2000 IU) per day during 2 months
Group usual treatment
No interventions assigned to this group
Interventions
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Zinc gluconate
Zinc gluconate capsule 15 mg x 2 per day during 2 months
25-OH cholecalciferol
25-OH cholecalciferol drinkable solution 10 drops (2000 IU) per day during 2 months
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Known hypercalcemia
* History of renal lithiasis
60 Years
ALL
No
Sponsors
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University Hospital, Lille
OTHER
Responsible Party
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Principal Investigators
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David SEGUY, MD,PhD
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Lille
References
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Shakoor H, Feehan J, Al Dhaheri AS, Cheikh Ismail L, Ali HI, Alhebshi SH, Apostolopoulos V, Stojanovska L. Role of vitamin D supplementation in aging patients with COVID-19. Maturitas. 2021 Oct;152:63-65. doi: 10.1016/j.maturitas.2021.03.006. Epub 2021 Mar 16. No abstract available.
Other Identifiers
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2020-A00873-36
Identifier Type: OTHER
Identifier Source: secondary_id
2020_30
Identifier Type: -
Identifier Source: org_study_id
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