Evaluation of Cold Forcep and Cold Snare Polypectomy for Polyps Less Than or Equal to 3mm in Size During Colonoscopy
NCT ID: NCT04551001
Last Updated: 2022-05-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
181 participants
INTERVENTIONAL
2020-09-16
2021-11-20
Brief Summary
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Detailed Description
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1. Experimental group: using cold forceps for polyps \<=3mm of the colon
2. Control group: using cold snare for polyps \<=3mm of the colon
3. Methods:
1. Colonoscopy will be performed in the same standard of care manner as if no study was taking place.
2. If polyps \<=3mm are identified, the endoscopist is randomized to performing polypectomy with cold forcep or cold snare.
3. After removal of the polypectomy, two biopsies are performed at the margin of the polypectomy site to identify residual lesion.
4. The polyp as well as well as the two biopsies are reviewed by a pathologist.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Cold forcep
Cold forcep polypectomy performed for polyps \<=3mm.
Cold forcep polypectomy
Removal of appropriate polyps using cold forceps until no polyp visible under white light. Two additional biopsies performed at margins of polypectomy site.
Cold snare
Cold forcep polypectomy performed for polyps \<=3mm.
Cold snare polypectomy
Removal of appropriate polyps using cold snare until no polyp visible under white light. Two additional biopsies performed at margins of polypectomy site.
Interventions
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Cold forcep polypectomy
Removal of appropriate polyps using cold forceps until no polyp visible under white light. Two additional biopsies performed at margins of polypectomy site.
Cold snare polypectomy
Removal of appropriate polyps using cold snare until no polyp visible under white light. Two additional biopsies performed at margins of polypectomy site.
Eligibility Criteria
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Inclusion Criteria
* Polyps \<=3mm
Exclusion Criteria
* Inflammatory bowel disease
* Polyposis syndromes
18 Years
ALL
Yes
Sponsors
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Stanford University
OTHER
Responsible Party
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Shai Friedland
Professor in Gastroenterology & Hepatology
Principal Investigators
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Shai Friedland, MD
Role: PRINCIPAL_INVESTIGATOR
Stanford University
Locations
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Veterans Affairs Palo Alto Health Care System
Palo Alto, California, United States
Countries
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References
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Wei MT, Louie CY, Chen Y, Pan JY, Quan SY, Wong R, Brown R, Clark M, Jensen K, Lau H, Friedland S. Randomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy Among Small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial. Am J Gastroenterol. 2022 Aug 1;117(8):1305-1310. doi: 10.14309/ajg.0000000000001799. Epub 2022 Apr 25.
Other Identifiers
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15766-1
Identifier Type: -
Identifier Source: org_study_id
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