Clinical Validation of Boneview for FDA Submission

NCT ID: NCT04532580

Last Updated: 2021-08-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

480 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-01

Study Completion Date

2021-07-26

Brief Summary

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The goal of this clinical validation is to assess comparative performances of physicians with and without the assistance of BoneView for the diagnosis of fractures on radiographs.

The performances are evaluated in terms of accuracy (primary endpoint with the pair specificity/sensitivity and the secondary endpoint PPV/NPV) and in terms of time needed for diagnosis (secondary endpoint with the measurement of time on each case).

Detailed Description

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Conditions

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Fracture

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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AI- Aided performances

Diagnosis of fracture on X-Ray Radiographs

Intervention Type DEVICE

Diagnosis of fracture on X-Ray Radiographs with and without the assistance of Boneview Software

AI- Unaided performances

Diagnosis of fracture on X-Ray Radiographs

Intervention Type DEVICE

Diagnosis of fracture on X-Ray Radiographs with and without the assistance of Boneview Software

Interventions

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Diagnosis of fracture on X-Ray Radiographs

Diagnosis of fracture on X-Ray Radiographs with and without the assistance of Boneview Software

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Anonymized standard X-ray exams of extremity/pelvis/rib cage/dorsolumbar spine not containing or containing fracture(s).
* Adult patient, with minimum age of 21 years old.

Exclusion Criteria

* Exams with one or more images including a body part not concerned by the intended use of BoneView (skull and cervical spine)
* Cases with one or more images being used for model design and development.
* Exams with one or more images being of poor quality (lossy), which prevent a proper interpretation by the readers.
* Cases not containing a medically relevant number of views for correct diagnosis.
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Gleamer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nor-Eddine Regnard, MD

Role: STUDY_CHAIR

Gleamer

Locations

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Boston Imaging Core Lab

Boston, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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BCK-CEP

Identifier Type: -

Identifier Source: org_study_id

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