Automated Bone Age Estimation From Noncontrast Abdominal CT Using Deep Learning

NCT ID: NCT07162168

Last Updated: 2025-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-01

Study Completion Date

2027-12-01

Brief Summary

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This study is a retrospective analysis that uses abdominal CT scans, which were originally taken for other medical reasons, to estimate bone age. By applying advanced deep learning methods, the investigators aim to develop a tool that can evaluate bone health and detect early signs of osteoporosis without requiring additional scans or radiation. This approach may help doctors better understand bone aging, improve screening for bone weakness, and provide patients with more personalized information about their bone health.

Detailed Description

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Conditions

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Bone Aging Osteoporosis Diagnosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Peking University People's Hospital cohort

No intervention

No interventions assigned to this group

Shandong Cohort

No intervention

No interventions assigned to this group

Canton Cohort

No intervention

No interventions assigned to this group

Guizhou cohort

No intervention

No interventions assigned to this group

Hunan Cohort

No intervention

No interventions assigned to this group

Inner Mongolia Cohort

No intervention

No interventions assigned to this group

Shaanxi Cohort

No intervention

No interventions assigned to this group

Shandong Cohort2

No intervention

No interventions assigned to this group

Other province Cohort

No intervention

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adults aged over 18 years.
* Underwent routine noncontrast abdominal CT scans.
* CT scans fully included the proximal femur.
* Scans were performed for non-orthopedic clinical indications.
* Provided necessary demographic information (e.g., age, sex).

Exclusion Criteria

* CT scans with poor image quality or severe artifacts that precluded accurate analysis.
* History of hip surgery or presence of internal fixation devices.
* Presence of bone tumors in the proximal femur.
* Severe hip deformity or prior fractures affecting the proximal femur.
* Pediatric patients or pregnant individuals (if applicable).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Peking University People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yuhui Kou

Research Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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CT machine

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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hanwen Cheng, M.D

Role: CONTACT

86-19541080926

Facility Contacts

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yuhui Kou, M.D

Role: primary

86-13146213332

Other Identifiers

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2024PHB388-001

Identifier Type: -

Identifier Source: org_study_id

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