Prevalence and Predictors of Osteoporosis in the Beijing's Urban Population

NCT ID: NCT01476150

Last Updated: 2011-11-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-31

Study Completion Date

2014-03-31

Brief Summary

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1. To establish a BMD reference database of Beijing's urban population, China.
2. To determine the prevalences and risk factors of osteoporosis and osteopenia in Beijing's urban population, China.
3. To describe the 25OHD level and estimate the prevalence of vitamin D insufficiency and deficiency of Beijing's urban population, China.
4. Estimation of the prevalence of osteoporotic fracture (vertebral) in over age of 60 of Beijing's urban population, China.

Detailed Description

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With one of the biggest populations in the world, China was heavily suffered from osteoporosis. The prevalence of osteoporosis in China even is increasing fast in recent years, which are especially notable in urban population. This change maybe due to the conditions including rapid economic growth, increase in life expectancy, and changes in lifestyle. Studies in 1998 including 13 separately small samples (no more than 1000 people) from 9 provinces in China showed that the prevalence of osteoporosis and osteopenia were 5.3-6.2% and 5.8-11.2%, respectively. These estimates were higher by approximately 1% than those reported in 1995. In 2002, according to DEXA results in connection with population census in 2000, Xiaoguang Cheng et al. took a survey in 600 people who were separately studied in previously 10 research projects and find that patients with osteoporosis account for approximately 6.97% of the total China population.

Although these studies have documented a remarkable increase in the prevalence of osteoporosis in China, these estimations were all based on small samples. No risk factors related with osteoporosis and osteopenia, esp. hypovitaminosis D on osteoporosis and osteopenia, have been analyzed yet. So it is impossible to make any forecast of osteoporosis or give any instruction for intervention.

Thus this study designed to provide current and reliable data on the prevalence of osteoporosis and osteopenia and associated risk factors correlation coefficients in the Beijing's urban adult population.

Conditions

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Osteoporosis

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Dongcheng

No interventions assigned to this group

Haidian

No interventions assigned to this group

Xicheng

No interventions assigned to this group

Chaoyang

No interventions assigned to this group

Chongwen

No interventions assigned to this group

Tongzhou

No interventions assigned to this group

Fengtai

No interventions assigned to this group

Xuanwu

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 20 to 79 residents in urban Beijing, China.
Minimum Eligible Age

20 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role collaborator

China-Japan Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Guochun Wang

Chief, Dept. of Rheumatology & Immunology, China-Japan Friendship Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Shukun Yao

Role: STUDY_CHAIR

China-Japan Friendship Hospital

Locations

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China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Central Contacts

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Huiqiong Zhou, MD., PhD.

Role: CONTACT

Phone: +86-10- 8420 5721

Email: [email protected]

Xia Liu, MD., PhD.

Role: CONTACT

Phone: +86-10- 8420 5721

Email: [email protected]

Facility Contacts

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Xia Liu, MD., PhD.

Role: primary

Other Identifiers

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CJFSRI-OP

Identifier Type: -

Identifier Source: org_study_id