Longitudinal Study of Primary Osteoporosis in Shanghai Postmenopausal Women

NCT ID: NCT02142348

Last Updated: 2014-05-20

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 3000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-06-30
• Study Completion Date: 2018-12-31

Brief Summary

To popularize knowledge of prevention and health care of osteoporosis.To investigate the prevalence of primary osteoporosis in community residents.

Detailed Description

1. Objective:

• To popularize knowledge of prevention and health care of osteoporosis.
• To investigate the prevalence of primary osteoporosis in community residents.

2. Method:

• The survey study included the five boroughs of six communities in Shanghai (Xuhui District 2, Pudong New Area 1, Minhang District 1, Pudong New Area 1, Jiading District 1). 10,000 participants are expected to be included.
• Through a questionnaire and physical examination form, carries on the investigation to the 50-85 years old postmenopausal women during the 3-year follow-up period.
• Make a survey of Bone Mineral Density,SF-36,international osteoporosis foundation ONE-MINUTE OSTEOPOROSIS RISK TEST,Markers of bone metabolism test,EQ-5D,Hepatic-renal function test and thyroid stimulating hormone level test.
• Physicians in each community as the backbone, Shanghai University of Traditional Chinese Medicine, Longhua Hospital is responsible for personnel training.
• Shanghai Clinical Research Center is responsible for program and data management.
• Shanghai District Health and Family Planning Commission is responsible for coordinating the organization.

Conditions

Primary Osteoporosis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

osteoprosis research

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Had clinical diagnosis of osteoporosis.
• With Bone Mineral Density by dual energy X-ray examination, T value <-2.5 or less.
• Be willing to and be able to join in the study and signed Informed consent.

Exclusion Criteria

• Excluding the impact of endocrine diseases of bone metabolism (gonadal, adrenal, parathyroid and thyroid disease), rheumatoid arthritis and other autoimmune diseases that affect the absorption of calcium and vitamin D and regulation of the digestive tract and kidney disease, multiple myeloma and other malignant diseases, long-term use of corticosteroids or other drugs affecting bone metabolism, and a variety of congenital and acquired diseases of bone metabolism.
• if they were unable to complete the study survey.

• Minimum Eligible Age: 50 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Shanghai University of Traditional Chinese Medicine

OTHER

Sponsor Role: lead

Responsible Party

Cui xuejun

Vice director

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Yongjun Wang, Dr

Role: PRINCIPAL_INVESTIGATOR

Study Principal Investigator Longhua Hospital

Locations

Longhua Hospital

Shanghai, Shanghai Municipality, China

Countries

China

Central Contacts

Xuejun Cui, Dr.

Role: CONTACT

13917715524@139.com

Facility Contacts

Xuejun Cui

Role: primary

13917715524@139.com

References

Xu H, Zhang H, Aimaiti R, Yuan C, Cai F, Wang H, Ji J, Liang J, Cui J, Wang J, Shu B, Xu H, Liang Q, Shi Q, Sun Q, Fang R, Tang D, Wang Y; China Community-based Cohort of Osteoporosis (CCCO) collaborative group. Early-life malnutrition exposure associated with higher osteoporosis risk in adulthood: a large-scale cross-sectional study. Int J Surg. 2025 Jan 1;111(1):190-199. doi: 10.1097/JS9.0000000000002057.

Reference Type: DERIVED

PMID: 39196877 (View on PubMed)

Other Identifiers

Shanghai OP Survey

Identifier Type: -

Identifier Source: org_study_id