Risk Factors for Acute Kidney Injury in Critically Ill Patients With Acute-on-Chronic Liver Failure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-01

Study Completion Date

2024-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Acute kidney injury (AKI) is one of the most important factors associated with increased mortality in patients with acute-on-chronic liver failure (AoCLF). Early identification and treatment of this subgroup of patients may improve survival and decrease ICU length of stay. As kidney ischemia is one of the main mechanisms responsible for AKI in AoCLF, an increase in urinary to arterial partial pressure of oxygen may help in the early diagnosis of renal failure. For this arterial and urinary oxygen pressure will be measured at ICU admission, on day 1 and day 3 of ICU stay. Diagnosis of AKI within the first 28 days after ICU admission will be recorded

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Prognostic Biomarkers For Acute Kidney Injury In Liver Cirrhosis

NCT03156426

Acute Kidney Injury Liver Cirrhoses Biomarkers

COMPLETED

Incidence and Outcomes of Acute Kidney Injury in Postoperative ICU Patients - a Retrospective Data Analysis

NCT04041323

Acute Kidney Injury ICU Postoperative Patients

COMPLETED

Transition of Acute Kidney Injury to Chronic Kidney Disease

NCT04101110

Acute Kidney Injury

COMPLETED

Follow-up of Long-term Renal Function After Acute Kidney Injury in ICU

NCT03302624

Acute Kidney Injuries Quality of Life Chronic Kidney Disease +1 more

UNKNOWN

Predictive Nomogram for Postoperative Acute Kidney Injury (AKI) in Elderly Patients Following Liver Resection

NCT04922866

Postoperative Acute Kidney Injury

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Acute Kidney Injury Acute-On-Chronic Liver Failure

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

\- patients admitted to the ICU for acute-on-chronic liver failure

Exclusion Criteria

* pre-existing renal disease
* urine output\<200 mL/day
* death within the first 24 hours after ICU admission
* emergency liver transplantation within the follow-up period (28 days)

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No