Outcomes of Acute Kidney Injury in Critically Ill Patients

NCT ID: NCT03338127

Last Updated: 2017-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-01

Study Completion Date

2018-06-30

Brief Summary

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this study to evaluate the frequency of acute kidney injury in critically ill patients in intensive care units.

Detailed Description

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Acute kidney injury (AKI) affects approximately 20% of hospitalized patients and up to 67% of those admitted to an intensive care unit (ICU), making it among the most common organ dysfunctions among the critically ill . Depending on severity, Acute kidney injury (AKI) contributes to short-perimortality rates between 40% and 70% , and survivors are at increased risk for chronic kidney disease (CKD) and late death.

The diagnosis of Acute kidney injury (AKI) is only considered after achieving an adequate status of hydration and after excluding urinary obstruction; Acute kidney injury (AKI) is defined by the sudden decrease (in 48 h) of renal function, defined by an increase in absolute serum creatinine of at least (0.3 mg/dL) or by a percentage increase in serum creatinine ≥50% (1.5× baseline value), or by a decrease in the urinary output (documented oliguria \<0.5 mL/kg/h for more than 6hours).

The purpose of this study was to benchmark the outcomes of acute kidney injury in a critically ill surgical patients.We hypothesized that renal dysfunction in this population is common and is associated with a significantly higher burden of morbidity, mortality, and resource utilization

Conditions

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Acute Kidney Injury

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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Participants

all patients recruited in the trial will be investigated for renal function test

renal function test

Intervention Type DIAGNOSTIC_TEST

2 ml blood sample to be investigated for renal function test

Interventions

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renal function test

2 ml blood sample to be investigated for renal function test

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

• All patient with acute kidney injury in critical care units in Luxor international hospital

Exclusion Criteria

* Patients on chronic dialysis
* Previous acute kidney injury
* Nephrectomy
* Organ transplant
* Chronic kidney disease
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alaa H Fahmy

OTHER

Sponsor Role lead

Responsible Party

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Alaa H Fahmy

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Ahmed M Aly, professor

Role: STUDY_DIRECTOR

professor of internal medicine

Central Contacts

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Alaa H Fahmy

Role: CONTACT

Phone: 00201118929161

Email: [email protected]

Other Identifiers

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AssiutU AHFahmy

Identifier Type: -

Identifier Source: org_study_id