Non-invasive Evaluation of the Predictive Value of CEUS and SWE in ACLF, Renal Failure and Hepatorenal Syndrome

NCT ID: NCT04446858

Last Updated: 2022-05-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2030-07-01

Brief Summary

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Evaluation of non-invasive prognostic parameters in patients developing ACLF and renal failure in patients receiving and not receiving transjugular intrahepatic portosystemic shunt (TIPS). Patients are cared according to the local standardized follow up program. Clinical and laboratory data from standard patient care are evaluated for potential prognostic value.

Detailed Description

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NECTAR consists of patients with ACLF and renal failure with and without receiving transjugular intrahepatic portosystemic shunt (TIPS) at the Department of Internal Medicine I, University of Bonn, Germany and receiving a structured routine evaluation and follow up program. The diagnosis of cirrhosis was based on clinical, hemodynamic and biochemical parameters, and ultrasound and/or biopsy criteria.

Conditions

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Kidney Failure, Acute

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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With TIPS

Prospective cohort that received TIPS

No interventions assigned to this group

Without TIPS

Prospective cohort that did not receive TIPS

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* All patients with portal hypertension and kidney failure

Exclusion Criteria

* no consent, no kidney failure, no portal hypertension
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Bonn

OTHER

Sponsor Role lead

Responsible Party

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Michael Praktiknjo

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Michael Praktiknjo, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Bonn

Locations

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University Hospital Bonn

Bonn, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Michael Praktiknjo, MD

Role: CONTACT

+49(0)228-287 15770

Johannes Chang, MD

Role: CONTACT

+49(0)228-287 15770

Facility Contacts

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Michael Praktiknjo, MD

Role: primary

+49228 28715770

Johannes Chang, MD

Role: backup

+49228 28715770

Other Identifiers

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NECTAR

Identifier Type: -

Identifier Source: org_study_id

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