Arterial Stiffness, Wave Reflections and Renal Failure

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

115 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-01-31

Study Completion Date

2010-10-31

Brief Summary

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1. Cardiovascular risk is high in patients with renal failure.
2. Cross-sectional studies have indicated a relationship between arterial stiffness and renal function. However, there are no prospective longitudinal studies in the literature.
3. In dialysis patients, arterial stiffness as well as wave reflections, predict mortality. However, there are no data on patients with mild-to-moderate renal impairment available.
4. Therefore, we designed a study to test the hypothesis that: a) measures of arterial stiffness and wave reflections predict the progression of renal impairment in patients with mild-to-moderate renal failure; and b) measures of arterial stiffness and wave reflections predict cardiovascular events in patients with mild-to-moderate renal failure

Detailed Description

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Conditions

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Chronic Renal Failure Arterial Stiffness Arterial Wave Reflections

Keywords

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chronic renal failure arterial stiffness arterial wave reflections

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* chronic renal failure patients (KDOQI III, IV) undergoing regular control visits at our nephrology department
* \> 19 years
* written informed consent

Exclusion Criteria

* atrial fibrillation
* valvular heart disease
* severely impaired systolic function
* no informed consent

Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Klinikum Wels-Grieskirchen

Principal Investigators

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Thomas Weber, MD

Role: PRINCIPAL_INVESTIGATOR

Cardiology Department, Klinikum Wels, Austria

Manfred Wallner, MD

Role: PRINCIPAL_INVESTIGATOR

Nephrology Department, Klinikum Wels, Austria

Locations

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Cardiology and Nephrology Department Klinikum Wels

Wels, , Austria

Site Status

Countries

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Austria

Other Identifiers

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WelsEK 206

Identifier Type: -

Identifier Source: org_study_id