Long-term Renal Prognosis of Neonatal Acute Kidney Injury

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

1852 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-01

Study Completion Date

2028-12-31

Brief Summary

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The goal of this observational study is to conduct a multicenter, prospective neonatal acute kidney injury (AKI) follow-up cohort to describe the clinical characteristics of chronic kidney disease (CKD) in AKI cases within 1 year of follow-up and screen for effective biomarkers that can early warn of CKD progression. Ultimately, a neonatal AKI adverse prognosis warning model based on multidimensional data will be established to provide new data and new models for CKD management.

Detailed Description

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Conditions

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Neonatal Acute Kidney Injury

Keywords

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Neonatal Acute Kidney Injury Long-Term Prognosis Prognosis and Predictive Factors Biomarkers

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Delivered in this hospital and subsequently admitted to the NICU during the study period;
* Diagnosed with neonatal AKI according to the 2015 KDIGO neonatal AKI criteria;
* Age \<28 days.

Exclusion Criteria

* Severe hydronephrosis diagnosed by prenatal renal ultrasound;
* Patients with congenital urinary malformations, including solitary kidney, cystic dysplasia, multicystic dysplastic kidney, renal dysplasia, and obstructive uropathy;
* Newborns who required congenital heart surgery within the first 7 days after birth;
* Newborns whose mothers had a history of renal failure;
* Death within 48 hours after birth;
* Other genetic syndromes or medical conditions were not eligible for inclusion according to the attending neonatologist's judgment.

Maximum Eligible Age

28 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Xia Gao

Role: CONTACT

Phone: 86-020-38370569

Email: [email protected]

Other Identifiers

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[2024]442A01

Identifier Type: -

Identifier Source: org_study_id