Study to Estimate How Common it is to Have Genetic Variants Associated With NAFLD

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

830 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-07

Study Completion Date

2022-10-10

Brief Summary

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The purpose of this study is to estimate the prevalence of genetic variants associated with liver disease in participants who are known, or are likely to have NAFLD.

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Detailed Description

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Conditions

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Healthy

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Healthy Participants

Healthy participants (men and women) who have, or are likely to have, NAFLD will be enrolled in the study.

No intervention

Intervention Type OTHER

No investigational medicinal product will be administered as a part of this study.

Interventions

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No intervention

No investigational medicinal product will be administered as a part of this study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* No clinically significant abnormality based on medical history, physical exam, and 12-lead electrocardiogram (ECG) collected during Visit 1
* Women must be of non-childbearing potential, defined as either: a.) Postmenopausal or b.) Permanently sterile
* Must be willing to provide a deoxyribonucleic acid (DNA) sample for assessment of genetic variants associated with NAFLD
* Must sign an informed consent form (ICF) indicating that he or she understands the purpose of, and procedures required for, the study and is willing to participate in the study

Exclusion Criteria

* History or presence of drug abuse within the 2 years prior to Visit 1
* Excessive use of alcohol within 2 years prior to the study
* Body mass index greater than (\>) 40 kilogram per meter square (kg/m\^2)
* Evidence of other active (acute or chronic) liver disease other than NAFLD/ Nonalcoholic steatohepatitis (NASH)
* History of bariatric surgery or planning to undergo bariatric surgery within the next year
* Inability to undergo magnetic resonance imaging (MRI)

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes