The Effects of Different Anesthesia Methods on Perioperative Neurocognitive Disorders in the Elderly
NCT ID: NCT04488952
Last Updated: 2022-04-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
350 participants
INTERVENTIONAL
2020-07-08
2024-06-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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nerve block combined with general anesthesia group
Patients in this group receive nerve block combined with general anesthesia.
nerve block combined with general anesthesia
Patients in this group receive nerve block combined with general anesthesia.
spinal anesthesia
Patients in this group receive spinal anesthesia.
spinal anesthesia group
Patients in this group receive spinal anesthesia.
nerve block combined with general anesthesia
Patients in this group receive nerve block combined with general anesthesia.
spinal anesthesia
Patients in this group receive spinal anesthesia.
control group
This group is used to obtain the learning effect.
nerve block combined with general anesthesia
Patients in this group receive nerve block combined with general anesthesia.
spinal anesthesia
Patients in this group receive spinal anesthesia.
Interventions
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nerve block combined with general anesthesia
Patients in this group receive nerve block combined with general anesthesia.
spinal anesthesia
Patients in this group receive spinal anesthesia.
Eligibility Criteria
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Inclusion Criteria
* ASA I-III
* Received elective surgery of unilateral lower extremity orthopedics
* The anesthesia lasted more than 2 hours
Exclusion Criteria
60 Years
85 Years
ALL
Yes
Sponsors
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Shenzhen Second People's Hospital
OTHER
Responsible Party
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ZhiHeng Liu
Chair of Department of Anesthesiology
Locations
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Shenzhen Second People's Hospital
Shenzhen, Guangdong, China
Countries
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Central Contacts
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Facility Contacts
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References
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Mason SE, Noel-Storr A, Ritchie CW. The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta-analysis. J Alzheimers Dis. 2010;22 Suppl 3:67-79. doi: 10.3233/JAD-2010-101086.
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Rasmussen LS, Johnson T, Kuipers HM, Kristensen D, Siersma VD, Vila P, Jolles J, Papaioannou A, Abildstrom H, Silverstein JH, Bonal JA, Raeder J, Nielsen IK, Korttila K, Munoz L, Dodds C, Hanning CD, Moller JT; ISPOCD2(International Study of Postoperative Cognitive Dysfunction) Investigators. Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients. Acta Anaesthesiol Scand. 2003 Mar;47(3):260-6. doi: 10.1034/j.1399-6576.2003.00057.x.
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Other Identifiers
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20193357001-XZ01
Identifier Type: -
Identifier Source: org_study_id
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