Effect of Sedatives on Perioperative Electroencephalogram in Elderly Patients Undergoing Spinal Anesthesia

NCT ID: NCT04248075

Last Updated: 2020-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-01

Study Completion Date

2021-02-28

Brief Summary

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In the present study, we observe perioperative findings of electroencephalogram in sedated and non-sedated elderly patients undergoing total knee arthroplasty under spinal anesthesia.

Detailed Description

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In the present study, we observe perioperative findings of electroencephalogram in sedated and non-sedated elderly patients undergoing total knee arthroplasty under spinal anesthesia. Electroencephalogram is performed before, during, and 1 day after surgery.

After the induction of anesthesia, sedation is performed according to the patient's request. If a patient want to be sedated during surgery, one of the three sedatives (dexmedetomidine, propofol, and midazolam) is administered.

Conditions

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Effect of Sedatives

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Control

Patients who do not want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery.

Electroencephalogram

Intervention Type DEVICE

Electroencephalogram is performed before, during, and 1 day after surgery in elderly patients undergoing spinal anesthesia.

Dexmedetomidine

Patients who want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery.

After the induction of spinal anestheisa, dexmedetomidine is administered for sedation during surgery.

Electroencephalogram

Intervention Type DEVICE

Electroencephalogram is performed before, during, and 1 day after surgery in elderly patients undergoing spinal anesthesia.

Propofol

Patients who want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery.

After the induction of spinal anestheisa, propofol is administered for sedation during surgery.

Electroencephalogram

Intervention Type DEVICE

Electroencephalogram is performed before, during, and 1 day after surgery in elderly patients undergoing spinal anesthesia.

Midazolam

Patients who want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery.

After the induction of spinal anestheisa, midazolam is administered for sedation during surgery.

Electroencephalogram

Intervention Type DEVICE

Electroencephalogram is performed before, during, and 1 day after surgery in elderly patients undergoing spinal anesthesia.

Interventions

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Electroencephalogram

Electroencephalogram is performed before, during, and 1 day after surgery in elderly patients undergoing spinal anesthesia.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Eldery patients scheduled for spinal anesthesia

Exclusion Criteria

* MMSE ≤ 23
* Hemodynamic unstability
* Liver disease
* Renal disease
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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SMG-SNU Boramae Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Jin-Young Hwang

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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20200120

Identifier Type: -

Identifier Source: org_study_id

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