Web Based CBT-I in Patients With OSA and Insomnia

NCT ID: NCT04473534

Last Updated: 2023-09-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-10

Study Completion Date

2022-03-30

Brief Summary

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Obstructive sleep apnea (OSA) and insomnia often occur in the same patient. Recent studies have demonstrated the efficacy of cognitive behavioral therapy (CBT-I) in patients with insomnia and OSA. Our aim is to verify the efficacy of web based CBT-I in patients with OSA and insomnia and the effect of web based CBT-I on the acceptance and adherence to CPAP (Continuous Positive Airway Pressure) therapy.

Detailed Description

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Obstructive sleep apnea is one of the most common sleep disorders with high prevalence in males sex, is often associated with insomnia. The presence of both sleep disorders generates a vicious circle that exacerbates the clinical picture, makes difficult to accept and adhere to CPAP therapy and increase cardiovascular risk. CBT-I is considered the best treatment for insomnia and recent research has demonstrated the efficacy of CBT-I also when insomnia is associated with OSA. After six month of treatment we will test the efficacy of web-based CBT-I in patients with OSA and insomnia in comparison to one session of psycho education on sleep, OSA, insomnia, the interaction among them and the influence on CPAP adherence.

Conditions

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Obstructive Sleep Apnea Insomnia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Arm of CBT-I treatment

Web cognitive behavioral therapy was administered before starting CPAP use by a psychologist expert in behavioral sleep medicine and expert in CBT-I. CBT-I was administered according to the same model and standard visual approach in patients with insomnia. Five sessions are scheduled: sleep psycho-education, sleep restriction, stimulus control, sleep hygiene and challenging beliefs and perception of sleep.

Group Type EXPERIMENTAL

web based cognitive-behavioral therapy

Intervention Type BEHAVIORAL

one web session of psycho-education about sleep

Arm of psycho-education session

Single session of psycho-education about sleep, OSA, insomnia and interaction among them will be administered by web before beginning CPAP use

Group Type EXPERIMENTAL

web based cognitive-behavioral therapy

Intervention Type BEHAVIORAL

one web session of psycho-education about sleep

Arm of control TAU (Treatment As Usual)

The control group will receive TAU. Each patient will start to use CPAP after the diagnosis according to AASM (American Academy of Sleep Medicine) guideline.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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web based cognitive-behavioral therapy

one web session of psycho-education about sleep

Intervention Type BEHAVIORAL

Other Intervention Names

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Arm of psycho-education session

Eligibility Criteria

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Inclusion Criteria

* Age ≥18
* Apnea-Hypopnea Index (AHI) ≥5

Exclusion Criteria

* Complex sleep apnea
* AHI \>35
* Psychiatric comorbidies
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituti Clinici Scientifici Maugeri SpA

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Fabio Rossato

Veruno, Novara, Italy

Site Status

Countries

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Italy

References

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Sweetman A, Lack L, Catcheside PG, Antic NA, Smith S, Chai-Coetzer CL, Douglas J, O'grady A, Dunn N, Robinson J, Paul D, Williamson P, McEvoy RD. Cognitive and behavioral therapy for insomnia increases the use of continuous positive airway pressure therapy in obstructive sleep apnea participants with comorbid insomnia: a randomized clinical trial. Sleep. 2019 Dec 24;42(12):zsz178. doi: 10.1093/sleep/zsz178.

Reference Type BACKGROUND
PMID: 31403168 (View on PubMed)

Sweetman A, McEvoy RD, Smith S, Catcheside PG, Antic NA, Chai-Coetzer CL, Douglas J, O'Grady A, Dunn N, Robinson J, Paul D, Williamson P, Lack L. The effect of cognitive and behavioral therapy for insomnia on week-to-week changes in sleepiness and sleep parameters in patients with comorbid insomnia and sleep apnea: a randomized controlled trial. Sleep. 2020 Jul 13;43(7):zsaa002. doi: 10.1093/sleep/zsaa002.

Reference Type BACKGROUND
PMID: 31927569 (View on PubMed)

Other Identifiers

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2361

Identifier Type: -

Identifier Source: org_study_id

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