MIND Diet Intervention and Cognitive Performance

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

37 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-26

Study Completion Date

2019-03-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This single-center, randomized trial examined the effect of MIND diet intervention on cognition and brain structure changes of healthy obese women over three months. The intervention group was lea to calorie-restricted modified by the MIND diet, and the control group received a calorie-restricted standard diet. The primary end-point was an assessment of cognitive performances measured with a comprehensive cognitive test battery. Secondary end-points were voxel-based morphometry to quantify the differences in brain structures. Our results revealed MIND diet could improve working memory, verbal recognition memory, and attention, more in comparison with the control group. Results also suggest that an increase in inferior frontal gyrus in the MIND diet group. Our study, for the first time, underlined that good adherence to the MIND diet as well as calorie restriction could reverse the destructive effect of obesity on cognition.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Impact of Mindfulness Program on Perceived Wellness, Eating Habits and Relationship to Food

NCT05233046

Diet, Healthy Food Habits Mental Fatigue +10 more

UNKNOWN NA

Weight Loss and Cognitive Function in Adults

NCT03685305

Overweight and Obesity

COMPLETED NA

Train Your Brain - Executive Function

NCT05938894

Overweight and Obesity

COMPLETED NA

Time Restricted Eating for Metabolic and Psychological Optimization

NCT05997316

Mild Cognitive Impairment Obesity

COMPLETED NA

The Effects of Diet on Mood, Cognition and Appetite

NCT01201616

Mild Cognitive Impairment

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Obesity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

calorie-restricted modified MIND diet

This arm received instruction in modifying the content of their diet to meet MIND pattern guidelines.

Group Type EXPERIMENTAL

New Dietary pattern ( Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND))

Intervention Type OTHER

A new brain-protection pattern that has been designed after the Mediterranean and DASH diet to improve some of their dietary factors to have the highest impact on brain health and cognitive performance.

calorie-restricted standard control diet

They instructed to calorie-restricted diet alone.

Group Type ACTIVE_COMPARATOR

New Dietary pattern ( Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND))

Intervention Type OTHER

A new brain-protection pattern that has been designed after the Mediterranean and DASH diet to improve some of their dietary factors to have the highest impact on brain health and cognitive performance.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

New Dietary pattern ( Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND))

A new brain-protection pattern that has been designed after the Mediterranean and DASH diet to improve some of their dietary factors to have the highest impact on brain health and cognitive performance.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Middle-aged women (40-60 years),
* Without any metabolic complication,
* BMI 30-35 kg/m2,
* MMSE ≥ 24,
* And no history of severe untreated medical, neurological, and psychiatric diseases which may interfere with the study intervention.

Exclusion Criteria

* Have gastrointestinal problems,
* Participate in weight loss programs,
* Use weight loss drugs in the last three months,
* Had not wholly followed the dietary pattern,
* Became pregnant,
* And undergo special medical treatments during a three months study.

Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes