Early Risk Stratification of Patient Hospitalized for SARS-CoV2 Infection: Critical COVID-19 France CCF

NCT ID: NCT04344327

Last Updated: 2020-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2878 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-10

Study Completion Date

2020-04-21

Brief Summary

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The COVID-19 pandemic of SARS CoV2 (Severe Acute Respiratory Syndrome, COVID-19) infection, which is currently evolving in France, raises many questions about the clinical and biological profile of infected hospitalized patients. If certain biological factors like troponin, BNP (Brain Natriuretic Peptid), or clinical factors like cardiovascular history or oncological history are associated with a worse prognosis, available data comes from studies in Asia for the majority, or including a limited number of patients. Patient stratification remains a major issue for patient sorting and early referral of patients.

Detailed Description

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This study is observational, multicenter and retrospective, and is conducted in hospitals in France.

Clinical data relating to history, comorbidities, risk factors, previous treatments, treatments during the hospitalization and treatments at the discharge from hospital, clinical parameters, biological and ultrasound cardiological data, procedures and events during hospitalization will be recorded, in order to identify the early predictors of clinical worsening in patients hospitalized for COVID-19 in cardiology or conventional medicine department.

Conditions

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Infection Viral Infection, Hospital COVID

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients with COVID-19

Patients hospitalized in conventional sector with diagnosis of COVID-19 (positive PCR (Polymerase Chain Reaction) or diagnosis presumed by the clinical and radiographic picture)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

\- Patients hospitalized in cardiology unit or medicine conventional sector with diagnosis of COVID-19 (positive PCR (Polymerase Chain Reaction) or diagnosis presumed by the clinical and radiographic picture)

Exclusion Criteria

* Minors
* Pregnant women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

Sponsor Role collaborator

French Cardiology Society

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Guillaume BONNET, MD

Role: STUDY_DIRECTOR

Hopital Européen Georges Pompidou

Orianne WEIZMAN, MD

Role: PRINCIPAL_INVESTIGATOR

Central Hospital, Nancy, France

Locations

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CHU d'Amiens

Amiens, , France

Site Status

CHU Annecy

Annecy, , France

Site Status

CHU de Bordeaux

Bordeaux, , France

Site Status

CHU de Caen

Caen, , France

Site Status

Cotentin hospital

Cherbourg, , France

Site Status

CHU Dijon

Dijon, , France

Site Status

Elbeuf Louviers Val de Reuil

Elbeuf, , France

Site Status

CHU de Fréjus / Saint-Raphael

Fréjus, , France

Site Status

Lille Catholic Institute Hospital Group, Lille

Lille, , France

Site Status

CHU de Lyon

Lyon, , France

Site Status

APHM

Marseille, , France

Site Status

Jacques Cartier Private Hospital, Massy

Massy, , France

Site Status

CHR d'Orléans

Orléans, , France

Site Status

Bichat (APHP)

Paris, , France

Site Status

Georges Pompidou European Hospital (AP-HP)

Paris, , France

Site Status

Institut Mutualiste Montsouris, Paris

Paris, , France

Site Status

CHU de Reims

Reims, , France

Site Status

CHU de Rouen

Rouen, , France

Site Status

CHU Saint Etienne

Saint-Etienne, , France

Site Status

CHU de Strasbourg

Strasbourg, , France

Site Status

CHU de Toulouse

Toulouse, , France

Site Status

Saint Gatien hospital

Tours, , France

Site Status

CHU de Nancy

Vandœuvre-lès-Nancy, , France

Site Status

Countries

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France

References

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Sutter W, Duceau B, Vignac M, Bonnet G, Carlier A, Roussel R, Trimaille A, Pommier T, Guilleminot P, Sagnard A, Pastier J, Weizman O, Giordano G, Cellier J, Geneste L, Panagides V, Marsou W, Deney A, Karsenty C, Attou S, Delmotte T, Ribeyrolles S, Chemaly P, Gautier A, Fauvel C, Chaumont C, Mika D, Pezel T, Cohen A, Potier L; Critical COVID-19 France Investigators. Association of diabetes and outcomes in patients with COVID-19: Propensity score-matched analyses from a French retrospective cohort. Diabetes Metab. 2021 Jul;47(4):101222. doi: 10.1016/j.diabet.2020.101222. Epub 2020 Dec 31.

Reference Type DERIVED
PMID: 33388386 (View on PubMed)

Other Identifiers

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2020-02

Identifier Type: -

Identifier Source: org_study_id

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