MYocardial DOmmages Related to COVID-19

NCT ID: NCT04498065

Last Updated: 2022-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

273 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-01

Study Completion Date

2022-05-31

Brief Summary

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Myocardial injury, as assessed by elevation of cardiac troponins (Tnc), is frequent among patients with COVID-19. Although rare autopsy cases reported COVID-19 related myocardial inflammation, the origin of Tnc elevation is unknown to date. Several cardiac causes, such as myocarditis, non-ischemic myocardial injury (NIMI), or myocardial infarction (MI) may lead to Tnc kinetic. Our work will test the hypothesis that during SARS-Cov2 infection, the elevation of cardiac biomarkers could be linked to the occurrence of myocarditis.

Detailed Description

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Conditions

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Covid19 Non Ischemic Myocardial Injury Myocardial Infarction Myocarditis Troponin Elevation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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A

COVID positive and Troponin positive

Biological data

Intervention Type BIOLOGICAL

Biological data

Clinical data

Intervention Type OTHER

Clinical data

B

COVID positive and Troponin negative

Biological data

Intervention Type BIOLOGICAL

Biological data

Clinical data

Intervention Type OTHER

Clinical data

Interventions

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Biological data

Biological data

Intervention Type BIOLOGICAL

Clinical data

Clinical data

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* COVID-19 positive patient hospitalized \< 72 h after symptoms onset with troponin assessement.

Exclusion Criteria

* patients hospitalized \> 72h after symptom onset
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire Dijon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Chu Dijon Bourgogne

Dijon, , France

Site Status

Countries

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France

Other Identifiers

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COTTIN AOIc 2020

Identifier Type: -

Identifier Source: org_study_id

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