Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant
NCT ID: NCT04319575
Last Updated: 2020-03-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE2/PHASE3
40 participants
INTERVENTIONAL
2018-12-03
2020-08-04
Brief Summary
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Detailed Description
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Methodology:
20 adult patients having periapical lesions in single rooted teeth were selected in this study after being assessed using the PAI index. Patients were randomly assigned to: Group - I (n=10) Chitosan with Ca (OH)2 and Group -II (n=10) Triple Antibiotic paste (TAP)
After access opening and cleaning and shaping were done in the first visit, the pertinent intracanal medicaments were placed depending on the patient group. After 4 weeks, on the second visit, the medicament was removed andobturation was done in the asymptomatic teeth. Both clinical and radiographic endodontic evaluation was done at 0, 3, 6 and 12months using the same parameters.
Radiographic evaluation was done using the PAI Index and was compared at 0, 3, 6, and 12 months after treatment, Z Test.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Chitosan calcium hyroxide paste
after the access preparation and cleaning and shaping, chitosan calcium hydroxide paste will be placed in the canal and kept for 4 weeks.
root canal treatment and intracanal medicament
after the access preparation and cleaning and shaping was done in 1st appointment using k files,"Mani" and protapers,"Dentsply" then in, chitosan calcium hydroxide paste," or ciprofloxacin metronidazole minocycline paste placed in the canal and kept for 4 weeks.
triple antibiotic paste
after the access preparation and cleaning and shaping, ciprofloxacin metronidazole minocycline paste will be :placed in the canal and kept for 4 weeks.
root canal treatment and intracanal medicament
after the access preparation and cleaning and shaping was done in 1st appointment using k files,"Mani" and protapers,"Dentsply" then in, chitosan calcium hydroxide paste," or ciprofloxacin metronidazole minocycline paste placed in the canal and kept for 4 weeks.
Interventions
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root canal treatment and intracanal medicament
after the access preparation and cleaning and shaping was done in 1st appointment using k files,"Mani" and protapers,"Dentsply" then in, chitosan calcium hydroxide paste," or ciprofloxacin metronidazole minocycline paste placed in the canal and kept for 4 weeks.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Roots with closed apex.
* Systemically healthy patients.
Exclusion Criteria
* Patients with a history of any systemic diseases.
* Pregnant and lactating women.
* Tooth associated with vertical root fracture and coronal perforation.
* Tooth affected with calcific degeneration.
* Presence of external or internal root resorption.
* Blunderbuss apex.
18 Years
40 Years
ALL
Yes
Sponsors
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Dr. D. Y. Patil Dental College & Hospital
OTHER
Responsible Party
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Soumya Shetty
professor
Principal Investigators
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Piyush D Oswal, MDS
Role: STUDY_DIRECTOR
Dr. D Y Patil Dental College, Pimpri, Pune
Locations
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Dr DY Patil Dental College And Hospital (DPU)
Pune, Maharashtra, India
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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DYPV/EC/55/16
Identifier Type: -
Identifier Source: org_study_id
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