Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
40 participants
INTERVENTIONAL
2016-03-31
2024-12-31
Brief Summary
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Detailed Description
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Group1: Calcium hydroxide-based antibacterial dressing - two session root canal treatment Group2: aPDT - one session root canal treatment Microbiological measurement. Filled with sterile PBS, the root canals were sampled immediately before and after the disinfection procedures.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Control group
Rubber dam isolation, tooth disinfection，acess to the pulp of the chamber, microbiological sample with two sterile paper points, then mechanical preparation with NITIMTWO to 25#06, and cleaned with 5 ml of 2.5% NaClO between each endodontic file. At the end of the procedure, root canals were ultrasonic irrigated with 2.5% NaClO, 17% EDTA for 1 min followed by irrigation with 0.9% normal saline to remove the smear layer, then take the sample again, drying the canal and fill the canal with a commercial calcium hydroxide-based paste. After 2 weeks, the canals were filled with AH-Plus sealer and Gutta-percha by vertical condensation. The teeth were take crown restoration. Follow up at 3, 6, 12 and 24 months.
Rubber dam isolation
tooth was isolated using a rubber dam in order to avoid the outside microbe
1% iodine tincture
use 1% iodine tincture to disinfect the crown of the teeth.in order to avoid the outside microbe
2.5%NaClO
use 2.5% NaClO as irrigants
root canal preparation
mechanical preparation with NITIMTWO to 25#06, and cleaned with 5 ml of 2.5% NaClO between each endodontic file. At the end of the procedure, root canals were ultrasonic irrigated with 2.5% NaClO, 17% EDTA for 1 min followed by irrigation with 0.9% normal saline to remove the smear layer
root canal obturation
filled the canals with AH-Plus sealer and Gutta-percha by vertical condensation
Experimental group
Rubber dam isolation，tooth disinfection，acess to the pulp of the chamber, microbiological sample with two sterile paper points, then mechanical preparation with NITIMTWO to 25#06, and cleaned with 5 ml of 2.5% NaClO between each endodontic file. At the end of the procedure, root canals were ultrasonic irrigated with 2.5% NaClO for 1 min, then 17%EDTA for 1 min followed by irrigation with 0.9% normal saline to remove the smear layer, drying the canal, aPDT, then take the sample again. then dried the canals and filled the canals with AH-Plus sealer and Gutta-percha by vertical condensation. The teeth were take crown restoration. Follow up at 3, 6, 12 and 24 months.
Rubber dam isolation
tooth was isolated using a rubber dam in order to avoid the outside microbe
aPDT
Inject the photosensitizer (PS)to the parallel orifice of the canal,use the small file to stir the PS for 60 s,then irradiation 120 s.
1% iodine tincture
use 1% iodine tincture to disinfect the crown of the teeth.in order to avoid the outside microbe
2.5%NaClO
use 2.5% NaClO as irrigants
root canal preparation
mechanical preparation with NITIMTWO to 25#06, and cleaned with 5 ml of 2.5% NaClO between each endodontic file. At the end of the procedure, root canals were ultrasonic irrigated with 2.5% NaClO, 17% EDTA for 1 min followed by irrigation with 0.9% normal saline to remove the smear layer
root canal obturation
filled the canals with AH-Plus sealer and Gutta-percha by vertical condensation
Interventions
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Rubber dam isolation
tooth was isolated using a rubber dam in order to avoid the outside microbe
aPDT
Inject the photosensitizer (PS)to the parallel orifice of the canal,use the small file to stir the PS for 60 s,then irradiation 120 s.
1% iodine tincture
use 1% iodine tincture to disinfect the crown of the teeth.in order to avoid the outside microbe
2.5%NaClO
use 2.5% NaClO as irrigants
root canal preparation
mechanical preparation with NITIMTWO to 25#06, and cleaned with 5 ml of 2.5% NaClO between each endodontic file. At the end of the procedure, root canals were ultrasonic irrigated with 2.5% NaClO, 17% EDTA for 1 min followed by irrigation with 0.9% normal saline to remove the smear layer
root canal obturation
filled the canals with AH-Plus sealer and Gutta-percha by vertical condensation
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
12 Years
60 Years
ALL
Yes
Sponsors
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Fujian Medical University
OTHER
Responsible Party
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Xiaojing Huang
DDS, PhD, Professor，Vice Dean，School and Hospital of Stomatology Fujian Medical University
Principal Investigators
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Xiaojing Huang, PhD
Role: STUDY_CHAIR
School and Hospital of stomatology,Fujian Medical University
Locations
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School and Hospital of stomatology,Fujian Medical University
Fuzhou, Fujian, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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YTYS83736434
Identifier Type: -
Identifier Source: org_study_id
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