Cortical-Basal Ganglia Speech Networks

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-10-01

Study Completion Date

2026-02-28

Brief Summary

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In this research study the researchers want to learn more about brain activity related to speech perception and production.

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Detailed Description

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Speech production is disrupted in a number of neurological diseases that involve the basal ganglia, including Parkinson's disease (PD) and dystonia. The investigators will use a novel experimental approach and combination of analytic techniques to elucidate the contribution of neural activity in cortical-basal ganglia circuits to the hierarchical control of speech production, in subjects undergoing deep brain stimulation surgery.

Conditions

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Parkinson Disease Essential Tremor Dystonia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Brain signal data collection

Brain signal data collection at the time of deep brain stimulation (DBS) surgery.

Group Type EXPERIMENTAL

electrophysiological data collection

Intervention Type OTHER

Electrophysiological data collection at the time of DBS surgery.

Interventions

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electrophysiological data collection

Electrophysiological data collection at the time of DBS surgery.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Subjects scheduled for DBS implantation, as determined by the clinical multidisciplinary movement disorders board with definitive diagnosis of Parkinson's disease, essential tremor or dystonia.
2. Subjects able to provide informed consent and comply with task instructions.
3. Subjects 18-85 years old