High Power vs Standard Power RF Ablation of Atrial Fibrillation in Conscious Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-11-15

Study Completion Date

2020-02-08

Brief Summary

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High RF energy ablation of atrial fibrillation is fast, safe, less painful and effective procedure.

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Detailed Description

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Atrial fibrillation (AF) ablation is the most commonly performed radiofrequency (RF) ablation and is usually associated with a long procedural time and sensation of pain in conscious patients. Prolonged radiation exposure during the procedure puts the patient and the operator at risk of malignancy and genetic abnormalities. Complications such as asymptomatic cerebral lesions, tamponade, perforation, and also arrhythmia recurrence were associated with longer ablation time.

High-power, shorter-duration radiofrequency ablation (HPSDRFA) appears to be a novel concept for atrial fibrillation (AF) but there are scarce data in conscious patients. The lesion side index (LSI) value has been associated with durability of pulmonary vein isolation (PVI) lesions.

We hypothesised that HPSDRFA applications based on the lesion side index (LSI; its has been associated with durability of pulmonary vein isolation (PVI) lesions) which were not inferior to standard approach regarding safety and effectiveness with shorten procedure time and being less painful for a patient.

Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Standard RF

ablation with RF power of 30 Watts (30W) and with 25 Watts (25W) on posterior wall

RF ablation of atrial fibrillation

Intervention Type OTHER

Comparison of standard, 40W and 50W RF energy setting for ablation of atrial fibrillation

High RF 40W (40 Watts)

ablation with RF power of 40 watts (40W)

RF ablation of atrial fibrillation

Intervention Type OTHER

Comparison of standard, 40W and 50W RF energy setting for ablation of atrial fibrillation

High RF 50W (50 Watts)

ablation with RF power of 50 watts (50W)

RF ablation of atrial fibrillation

Intervention Type OTHER

Comparison of standard, 40W and 50W RF energy setting for ablation of atrial fibrillation

Interventions

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RF ablation of atrial fibrillation

Comparison of standard, 40W and 50W RF energy setting for ablation of atrial fibrillation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* symptomatic patients with non-valvular AF,
* aged:18-85, first procedure in left atrium,
* exclusion of thrombus in left atrium and left atrium appendage,
* left ventricle ejection fraction \>55%