Real Zero Fluoroscopy Catheter Ablation.

NCT ID: NCT03458273

Last Updated: 2018-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-10

Study Completion Date

2018-12-31

Brief Summary

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A Retrospective Propensity Matched Study comparing:

* real zero fluoroscopy catheter ablation
* conventional fluoroscopy catheter ablation without 3D system
* conventional fluoroscopy catheter ablation with 3D system

Detailed Description

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Catheter ablation is a well-established treatment to treat patients with a wide scope of heart arrhythmias.

The study is an investigator-initiated, retrospective analysis of prospectively collected data. The study population consists of patients with right-sided arrhythmias who underwent zero-fluoroscopy catheter ablation between the years 2016 and 2018 in 3 centers and a propensity score matched patients group of patients who:

* underwent conventional fluoroscopy guided catheter ablation without 3D system (Ensite/Carto) support
* underwent conventional fluoroscopy guided catheter ablation with 3D system (Ensite/Carto) support

Covariates for matching will be:

* arrhythmia type
* age of a patient
* number of diagnostic catheters used during a procedure
* type of a diagnostic catheter used during a procedure\]

Conditions

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Atrial Arrhythmia Ventricular Arrythmia Arrhythmia Arrhythmias, Cardiac

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Zero fluoro

Patients in whom Zero fluoroscopy ablation was performed under the guidance of Ensite for mapping and ablation and fluoroscopy will not be used during the procedure.

Zero fluoroscopy ablation

Intervention Type PROCEDURE

Catheter ablation for the treatment of atrial and ventricular arrhythmia - no fluoroscopy guidance

Conventional ablation without 3D

Patients in whom Conventional fluoroscopy ablation was performed under fluoroscopic guidance only.

Additional use of Ensite/Carto/Localisa for mapping was not allowed.

Conventional ablation without 3D

Intervention Type PROCEDURE

Catheter ablation for the treatment of atrial and ventricular arrhythmia - fluoroscopy guidance only. 3D system (Every Ensite/Carto) is not allowed

Conventional ablation with 3D

Patients in whom Conventional fluoroscopy ablation was performed under fluoroscopic and Ensite/Carto guidance and ablation during the procedure.

Use of fluoroscopy and additional Ensite/Carto for mapping and ablation was mandatory.

Conventional ablation with 3D

Intervention Type PROCEDURE

Catheter ablation for the treatment of atrial and ventricular arrhythmia - fluoroscopy guidance + 3D system support (Ensite/Carto)

Interventions

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Zero fluoroscopy ablation

Catheter ablation for the treatment of atrial and ventricular arrhythmia - no fluoroscopy guidance

Intervention Type PROCEDURE

Conventional ablation without 3D

Catheter ablation for the treatment of atrial and ventricular arrhythmia - fluoroscopy guidance only. 3D system (Every Ensite/Carto) is not allowed

Intervention Type PROCEDURE

Conventional ablation with 3D

Catheter ablation for the treatment of atrial and ventricular arrhythmia - fluoroscopy guidance + 3D system support (Ensite/Carto)

Intervention Type PROCEDURE

Other Intervention Names

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Zero fluoro Conventional fluoroscopy ablation without 3D Conventional fluoroscopy ablation with 3D

Eligibility Criteria

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Inclusion Criteria

* right atrial tachycardia
* right atrial premature complexes
* AVNRT
* right atrial AVRT/WPW
* right ventricle tachycardia / right ventricle premature complexes

Exclusion Criteria

* left atrium arrhythmia
* left ventricle arrhythmia
Minimum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical University of Lublin

OTHER

Sponsor Role lead

Responsible Party

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Maciej Wójcik, MD, PhD

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Maciej Wójcik, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Medical University of Lublin, Poland

Locations

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Wojewódzki Szpital Specjalistyczn

Biała Podlaska, , Poland

Site Status RECRUITING

Medical University of Lublin

Lublin, , Poland

Site Status RECRUITING

SP ZOZ Szpital Puławy

Puławy, , Poland

Site Status RECRUITING

Countries

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Poland

Central Contacts

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Maciej Wójcik, MD, PhD

Role: CONTACT

+48817244151

Facility Contacts

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Maciej Wójcik, MD,PhD

Role: primary

+48817244151

Maciej Wójcik, MD, PhD

Role: primary

+48817244151

Maciej Wójcik, MD, PhD

Role: primary

+48817244151

References

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Yang L, Sun G, Chen X, Chen G, Yang S, Guo P, Wang Y, Wang DW. Meta-Analysis of Zero or Near-Zero Fluoroscopy Use During Ablation of Cardiac Arrhythmias. Am J Cardiol. 2016 Nov 15;118(10):1511-1518. doi: 10.1016/j.amjcard.2016.08.014. Epub 2016 Aug 24.

Reference Type BACKGROUND
PMID: 27639689 (View on PubMed)

Casella M, Ribatti V, Catto V, Vettor G, Fassini G, Biagioli V, Dello Russo A, Tondo C. Benefits of electroanatomic ablation of conventional cardiac arrhytmias: from fluoroscopy to zero X-ray mapping. Minerva Cardioangiol. 2018 Feb;66(1):49-62. doi: 10.23736/S0026-4725.17.04478-4. Epub 2017 Aug 31.

Reference Type BACKGROUND
PMID: 28862408 (View on PubMed)

Gaita F, Guerra PG, Battaglia A, Anselmino M. The dream of near-zero X-rays ablation comes true. Eur Heart J. 2016 Sep 21;37(36):2749-2755. doi: 10.1093/eurheartj/ehw223. Epub 2016 Jun 26.

Reference Type BACKGROUND
PMID: 27354053 (View on PubMed)

Seizer P, Bucher V, Frische C, Heinzmann D, Gramlich M, Muller I, Henning A, Hofbeck M, Kerst G, Gawaz M, Schreieck J. Efficacy and safety of zero-fluoroscopy ablation for supraventricular tachycardias. Use of optional contact force measurement for zero-fluoroscopy ablation in a clinical routine setting. Herz. 2016 May;41(3):241-5. doi: 10.1007/s00059-015-4358-4. Epub 2015 Oct 13.

Reference Type BACKGROUND
PMID: 26462477 (View on PubMed)

Bulava A, Hanis J, Eisenberger M. Catheter Ablation of Atrial Fibrillation Using Zero-Fluoroscopy Technique: A Randomized Trial. Pacing Clin Electrophysiol. 2015 Jul;38(7):797-806. doi: 10.1111/pace.12634. Epub 2015 Apr 16.

Reference Type BACKGROUND
PMID: 25790320 (View on PubMed)

Scaglione M, Ebrille E, Clemente FD, Gaita F, Bradfield JS. Catheter Ablation of Atrial Fibrillation Without Radiation Exposure Using A 3D Mapping System. J Atr Fibrillation. 2015 Feb 28;7(5):1167. doi: 10.4022/jafib.1167. eCollection 2015 Feb-Mar.

Reference Type BACKGROUND
PMID: 27957146 (View on PubMed)

Alvarez M, Bertomeu-Gonzalez V, Arcocha MF, Morina P, Tercedor L, Ferrero de Loma A, Pachon M, Garcia A, Pardo M, Datino T, Alonso C, Osca J; investigators of the Spanish Multicenter Registry of Fluoroscopy-free Ablation. Nonfluoroscopic Catheter Ablation. Results From a Prospective Multicenter Registry. Rev Esp Cardiol (Engl Ed). 2017 Sep;70(9):699-705. doi: 10.1016/j.rec.2016.12.040. Epub 2017 Jan 31. English, Spanish.

Reference Type RESULT
PMID: 28159569 (View on PubMed)

Other Identifiers

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MW-MULublin-2

Identifier Type: -

Identifier Source: org_study_id

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