At-home Transcranial Alternating Current Stimulation During Multitasking

NCT ID: NCT04231825

Last Updated: 2022-03-21

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

47 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-15

Study Completion Date

2020-09-15

Brief Summary

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The goal is to replicate in-lab results from transcranial alternating current stimulation (tACS) with at-home tACS.

Detailed Description

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Participants will be assessed in-lab on multitasking and sustained attention abilities. Participants will be sent home with a tACS device to be used at-home for five days while engaged in a multitasking paradigm that is different from the multitasking outcome measure used pre/post tACS. After the at-home stimulation is complete, participants return to UCSF for a final in-lab assessment of multitasking and sustained attention ability.

Conditions

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Multitasking Behavior

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Verum Stimulation

This group will receive 6-Hz tACS

Group Type EXPERIMENTAL

Transcranial alternating current stimulation

Intervention Type DEVICE

Transcranial alternating current stimulation across the prefrontal cortex using electrodes F3 and F4.

Frequency Control

This group will receive 1-Hz tACS

Group Type ACTIVE_COMPARATOR

Transcranial alternating current stimulation

Intervention Type DEVICE

Transcranial alternating current stimulation across the prefrontal cortex using electrodes F3 and F4.

Interventions

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Transcranial alternating current stimulation

Transcranial alternating current stimulation across the prefrontal cortex using electrodes F3 and F4.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* English speaking
* Grade 12 or more education
* Normal or corrected to normal vision and hearing
* Ability to complete cognitive tasks
* Ability to cooperate and comply with all study procedures
* Ability to tolerate tACS

Exclusion Criteria

* Neurological or psychiatric disorders
* Family history of epilepsy
* History of seizures
* Prior head trauma
* Pregnant
* Implanted electronic devices (e.g., pacemaker)
* IQ \< 80
* Taking psychotropic medication
* Taking anti-depressants or anti-anxiety medication
* Substance abuse
* Color blind
* Glaucoma
* Macular degeneration
* Amblyopia
* Strabismus
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of California, San Francisco

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Theodore Zanto, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of California, San Francisco

Locations

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Sandler Neurosciences Center

San Francisco, California, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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18-26268-1

Identifier Type: -

Identifier Source: org_study_id

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