Dietary Practices and Metabolic Syndrome in the Young Adult Population of Rwanda

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1247 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-01

Study Completion Date

2023-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Policy makers in Rwanda have recently highlighted the importance of promoting healthy diets and lifestyle in response to rapidly increasing rates of obesity. This project will provide evidence on shifts in diet and nutritional status in urban dwellers as compared to the traditional diet and lifestyle in rural areas as a basis for a targeted public health policy for Rwanda.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Medical Interventions in Insulin Resistance on Prevalence of Abnormal Glucose Tolerance

NCT02502344

Insulin Resistance

UNKNOWN PHASE4

Clinical Effects of Nutrition on Metabolic Risk Factors and Mechanisms

NCT02405806

Obesity Diet Modification

COMPLETED NA

Impact of Exercise on the Metabolic Consequences of Overeating

NCT02701738

Healthy

COMPLETED NA

Effect of Feeding Frequency on Glucose and Insulin Metabolism and Substrate Partitioning

NCT01034293

Insulin Glucose Metabolism

COMPLETED NA

The Effects of Calorie Restriction With or Without Metformin on Weight and Insulin Resistance

NCT00134290

Body Weight Insulin Resistance

COMPLETED PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Adequate diet has been known for many years to be a major lever to significantly decrease the risk for non-communicable diseases (NCD). However, mainly due to urbanization and improved economic status in low and middle income countries (LMICs), the traditional largely plant-based diets are being replaced by more energy-dense and nutrient poor diets, incorporating more animal foods and processed foods and fat, and with a decrease in consumption of fruits and vegetables and other plant based foods. This diet change together with a sedentary lifestyle are typical phenomena in LMICs that are driving the so-called nutrition transition that is typically accompanied by an increase in obesity and in NCD like metabolic syndrome, diabetes, cardiovascular diseases and cancer. In Rwanda, NCD lead to 36% of total deaths. Cancers, diabetes, cardiovascular diseases, and chronic respiratory diseases account for 82% of NCD deaths. The major risk factor is the raised blood pressure (34.4%) and the probability of dying between ages 30 and 70 years from those four main NCD is estimated to 19%.

The Government of Rwanda has installed an operational NCD unit in the Ministry of Health with a view to developing preventive strategies vis-à-vis the nutrition transition process in the country. It has been shown already that there is a need for adopting dietary behaviour change to prevent the epidemic of chronic diseases.

The aim of this PhD work is to contribute in generating evidence needed to develop targeted prevention strategies for NCD in a broader framework of informed health policy making in Rwanda.

Specific objectives:

1. To identify the changes in eating habits of different socio- economic subgroups in adults living in Kigali, in comparison to their peers in rural areas;
2. To assess nutritional status and body composition using several methods (BMI, skinfold thicknesses, sitting height and body build, fat and fat free mass), with the ultimate objective to establish population-body composition-derived BMI cut-offs for overweight and obesity in this population;
3. To assess and compare the prevalence of common risk factors for non-communicable disease (high BMI, low fruit and vegetable consumption, low physical activity and high blood pressure) between rural and urban areas;
4. To evaluate people's nutrition knowledge, aptitude and capacity (KAP), perception of obesity and normal weight and food insecurity levels as risks factors for adherence to healthy dietary practices and life style;
5. To generate information to be used by governments to improve dietary habits and physical activity through targeted interventions.

The data collected in a cross sectional study design. Validated questionnaires will be used to get information on socio-economic characteristics, dietary practices, physical activity, other lifestyle factors and psycho-social and emotional indicators.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Metabolic Syndrome Nutritional Status Diet Habit

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Urban

Young adults living in urban communities of Rwanda

Dietary habits

Intervention Type OTHER

Data collected using food frequency questionnaire

Risk factors associated with metabolic syndrome

Intervention Type OTHER

Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome

Rural

Young adults living in rural communities of Rwanda

Dietary habits

Intervention Type OTHER

Data collected using food frequency questionnaire

Risk factors associated with metabolic syndrome

Intervention Type OTHER

Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Dietary habits

Data collected using food frequency questionnaire

Intervention Type OTHER

Risk factors associated with metabolic syndrome

Data collected on nutritional status, biochemical indicators and other risk factors associated with metabolic syndrome

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Permanent residence of the selected urban or rural villages
* Holding a valid health insurance card
* Aged between 18 and 35 years
* Signing informed consent form
* Registration in city demographic system, since study participants will be selected from population registration cards at village level,
* Accept enumerators for home visit and data collection
* Accept to visit the laboratory for blood sample collection,
* Not suffering from any chronic disease such as VIH/ AIDS, diabetes, asthma, etc.

Exclusion Criteria

* Lactating, pregnant, and recently delivering (less than six month-postpartum) women
* Physical disabilities that can prevent participants from working
* Mental disability such as clinically diagnosed depression, anxiety disorders, eating disorders and addictive behaviors.

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes