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Definition of ARDS in Qinghai Province: Verification of Berlin Definition Plateau Criteria

NCT ID: NCT04199650

Last Updated: 2019-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

253 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-04-01

Study Completion Date

2020-08-30

Brief Summary

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The severity stratification criteria for acute respiratory distress syndrome (ARDS) in Xi'ning Qinghai province (mean altitude: 2200m) were clarified according to the oxygenation index (PaO2/FiO2).

Detailed Description

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This study is a single-center retrospective study. According to the Berlin diagnostic standard, ARDS patients admitted to the Department of severe Medicine, affiliated Hospital of Qinghai University from January 2018 to December 2018 were divided into three groups: mild (153mmHg \< PaO2/ FiO2 ≥ 230 mmHg), moderate (76mmHg \< PaO2/ FiO2 ≥ 153 mmHg) and severe (PaO2/ FiO2 ≥ 76 mmHg). The ICU mortality, 28-day mortality, non-ventilator time in ICU, ICU hospitalization time and non-I hospitalization were observed respectively. The difference of CU time and total hospitalization days.

Conditions

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ARDS High Altitude

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

OTHER

Study Groups

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Mild ARDS

153mmHg\<PaO2/FiO2≤230mmHg

No interventions assigned to this group

Moderate ARDS

76mmHg\<PaO2/FiO2≤153mmHg

No interventions assigned to this group

Severe ARDS

PaO2/FiO2≤76mmHg

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 18 years of age
* Meet the diagnostic criteria of ARDS
* Receive invasive mechanical ventilation

Exclusion Criteria

* Receive a large number of hormone shock therapy in a short period of time
* Death within a short period of time (\< 24 h) after mechanical ventilation
* No chest imaging data
* Data missing
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Affiliated Hospital of Qinghai University

OTHER

Sponsor Role collaborator

Southeast University, China

OTHER

Sponsor Role lead

Responsible Party

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Chun Pan

Deputy chief physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Liu Xiaoqin, Bachelor

Role: PRINCIPAL_INVESTIGATOR

Affiliated Hospital of Qinghai University

Locations

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ChunPan

Nanjing, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Gan Guifen, Bachelor

Role: CONTACT

Phone: 15897083336

Email: [email protected]

Pan Chun, Doctor

Role: CONTACT

Phone: 13814009925

Email: [email protected]

Facility Contacts

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Guifen Gan, Bachelor

Role: primary

Xiaoqin Liu, Bachelor

Role: backup

References

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Liu X, Pan C, Si L, Tong S, Niu Y, Qiu H, Gan G. Definition of Acute Respiratory Distress Syndrome on the Plateau of Xining, Qinghai: A Verification of the Berlin Definition Altitude-PaO2/FiO2-Corrected Criteria. Front Med (Lausanne). 2022 Feb 23;9:648835. doi: 10.3389/fmed.2022.648835. eCollection 2022.

Reference Type DERIVED
PMID: 35280910 (View on PubMed)

Other Identifiers

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ARDS Plateau Criteria

Identifier Type: -

Identifier Source: org_study_id