Explore Potential Plasma and BALF Immunometabolic and Lipidomic Biomarkers for Identifying ARDS Endotypes
NCT ID: NCT05451342
Last Updated: 2022-07-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
200 participants
OBSERVATIONAL
2022-02-15
2024-06-15
Brief Summary
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Detailed Description
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This is an observational study. The blood and BALF samples will be collected from patients with ARDS for exosome extraction and transcriptome and metabolomic analysis.
Exosome characterization and differential genes and metabolites will be identified.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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ARDS
Patients who meet the diagnostic criteria of ARDS
Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling
Blood samples and BALD samples will be collected for further integrated transcriptomics, metabolomics, lipidomics analysis, and exosome extraction.
Non-ARDS
Patients without ARDS
Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling
Blood samples and BALD samples will be collected for further integrated transcriptomics, metabolomics, lipidomics analysis, and exosome extraction.
Interventions
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Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling
Blood samples and BALD samples will be collected for further integrated transcriptomics, metabolomics, lipidomics analysis, and exosome extraction.
Eligibility Criteria
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Inclusion Criteria
2. Meet the diagnostic criteria of ARDS according to the Berlin Criteria.
Exclusion Criteria
2. Pregnancy;
3. No informed consent;
18 Years
ALL
No
Sponsors
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Peking Union Medical College Hospital
OTHER
Responsible Party
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Principal Investigators
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Yun Long, MD
Role: STUDY_DIRECTOR
Peking Union Medical College
Locations
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PUMC
Beijing, Beijing Municipality, China
Yingying Yang
Beijing, Beijing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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ZS-3391
Identifier Type: -
Identifier Source: org_study_id
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