The Value of Serum MicroRNA-21-5p and LncRNAgadd7 Expression Levels in Predicting the Severity and Prognosis of ARDS ( Acute Respiratory Distress Syndrome )

NCT ID: NCT06825754

Last Updated: 2025-02-13

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 110 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-11-01
• Study Completion Date: 2025-01-10

Brief Summary

By measuring the expression levels of MicroRNA-21-5p (miR-21-5p) and LncRNAgadd7 in the peripheral blood of ARDS patients, the study aims to explore the correlation between these levels and the severity and prognosis of ARDS.

Conditions

Acute Respiratory Distress Syndrome

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

Survival Group

No interventions assigned to this group

Death Group

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

1. Age ≥ 18 years;

2. Meets the Berlin Criteria for ARDS;

3. Diagnosed with ARDS within 48 hours;

4. Signed informed consent.

Exclusion Criteria

1. Immunosuppressed patients: including those on immunosuppressive drugs, history of stem cell transplantation, etc.;

2. Patients with malignant tumors;

3. Pregnant women;

4. Patients discharged from the ICU within 48 hours;

5. History of chronic lung diseases.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Shao Yuekai

OTHER

Sponsor Role: lead

Responsible Party

Shao Yuekai

Researcher

Responsibility Role: SPONSOR_INVESTIGATOR

Locations

Affiliated Hospital of Zunyi Medical University

Zunyi, Guizhou, China

Countries

China

Other Identifiers

KLLY-2023--198

Identifier Type: -

Identifier Source: org_study_id