Intestinal Perforation in Patients Receiving an Orthtopic Liver Transplantation in the Montpellier University Hospital

NCT ID: NCT04180735

Last Updated: 2019-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-30

Study Completion Date

2019-10-30

Brief Summary

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Liver transplantation enhances the prognosis of patients with cirrhoses or hepatocellular carcinoma. However some patients develop intestinal perforations for which the prognosis is poor.

The aim of the study is to evaluate the risk factors of intestinal perforations using a retrospective study scheme.

Detailed Description

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Liver transplantation enhances the prognosis of patients with cirrhoses or hepatocellular carcinoma. However some patients develop intestinal perforations for which the prognosis is poor.

The aim of the study is to evaluate the risk factors of intestinal perforations using a retrospective study scheme. Previous studies have shown a possible implication of drugs or medical history or intraoperative complications. The investigators aim to describe the other possible risk factors (such as portal vein clampage) and the type of surgery done after the diagnosis and its impact on survival as well.

Conditions

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Liver Transplantation Intestinal Perforation Digestive System Fistula Intestinal Fistula

Keywords

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Risk Factors Survival

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Perforation

Perforation

Liver transplantation

Intervention Type PROCEDURE

Liver transplantation

No perforation

No perforation

Liver transplantation

Intervention Type PROCEDURE

Liver transplantation

Interventions

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Liver transplantation

Liver transplantation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients having received an orthotopic liver transplantation in the Montpellier University Hospital from 2014 to 2019
* for the group Perforation: patients having during the follow-up a complication such as intestinal perforation. The complete list uses the ICD-10 codes for intestinal perforation, esophageal perforation, duodenal perforation etc.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Université Montpellier

OTHER

Sponsor Role collaborator

University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Fabrizio PANARO, PhD

Role: STUDY_DIRECTOR

UH MONTPELLIER

Locations

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Uh Montpellier

Montpellier, , France

Site Status

Countries

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France

Other Identifiers

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RECHMPL19_0362

Identifier Type: -

Identifier Source: org_study_id