Intracorporeal Versus Extracorporeal Technique for Ileocolic Anastomosis in Laparoscopic Right Hemicolectomy

NCT ID: NCT03934151

Last Updated: 2019-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1225 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-01

Study Completion Date

2018-12-15

Brief Summary

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The aim of the study is to analyze the postoperative complication rate of intracorporeal versus extracorporeal anastomotic technique in laparoscopic or video assisted right hemicolectomy for malignant and benign neoplasms . The lead center is the General and Thoracic Surgery Department of the University of Ferrara. Prof. Anania is the responsible for the enrollment of patients and the coordination with the collaborating centers in the six month-study

Detailed Description

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CoDIG is a cohort, observational, prospective, multi-centric national study about ileo-colic anastomosis performing with EC or IC Technique during right laparoscopic hemicolectomy.

The observational period lasts from march 2018 and September 2018. The promoter of the study is "Istituto di Chirurgia Generale 1" of Ferrara University Hospital.

135 Italian Hospitals, accredited by Health Ministry, have been contacted via e-mail and all data was compiled into a web accessible SICE database, 85 Italian clinical centres, with demonstrated experience in colorectal laparoscopic surgery, have joined the study.

Every centre was asked not to change its surgical habits concerning the technologies used, the surgical approach, the anastomotic method, the post-operative management.

Every patient involved into the study was asked to sign a consent form in order to the Helsinki Declaration.

Conditions

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Complication of Gastrointestinal Anastomosis Intestinal Anastomosis Complication

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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intracorporeal anastomosis

patients who underwent elective right hemicolectomy whose ileocolic anastomosis was performed with intracorporeal technique

intracorporeal ileocolic anastomosis

Intervention Type PROCEDURE

laparoscopic bowel transection and ileocolic anastomosis performed inside the abdomen with specimen retrieval in plastic bag

extracorporeal anastomosis

patients who underwent elective right hemicolectomy whose ileocolic anastomosis was performed with extracorporeal technique

extracorporeal ileocolic anastomosis

Intervention Type PROCEDURE

ileocolic anastomosis is carried out by exteriorizing the bowel through a limited laparotomy

Interventions

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intracorporeal ileocolic anastomosis

laparoscopic bowel transection and ileocolic anastomosis performed inside the abdomen with specimen retrieval in plastic bag

Intervention Type PROCEDURE

extracorporeal ileocolic anastomosis

ileocolic anastomosis is carried out by exteriorizing the bowel through a limited laparotomy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients and/or legal guardians exhaustively informed by the investigator, and who have voluntarily provided written informed consent or, when unable to read and/or write, verbal consent put into writing by a third person
* Patients who underwent elective laparoscopic or video assisted right hemicolectomy at U.O. General and Thoracic Surgery for malignant or bening pathology.
* Patients who had prior chemotherapy and radiotherapy

Exclusion Criteria

* Patients operated in emergency
* Pregnant women
* Right laparotomic hemicolectomy
* BMI\> 35
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital of Ferrara

OTHER

Sponsor Role lead

Responsible Party

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Gabriele Anania

Professore Associato

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gabriele Anania

Role: PRINCIPAL_INVESTIGATOR

Società Italiana Chirurgia Endoscopica

Locations

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ULSS5 Polesa - Ospedale di Adria

Adria, , Italy

Site Status

San Lazzaro Alba

Alba, , Italy

Site Status

Ospedale Civile L. Bonomo

Andria, , Italy

Site Status

"U.Parini" di AOsta

Aosta, , Italy

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Ospedale C e G Mazzoni

Ascoli Piceno, , Italy

Site Status

Casa di Cura Villa Maria

Avellino, , Italy

Site Status

Ospedale di Bassano del Grappa

Bassano del Grappa, , Italy

Site Status

Policlinico San Marco

Bergamo, , Italy

Site Status

Ospedale Maggiore di Bologna

Bologna, , Italy

Site Status

SS. Pietro e Paolo

Borgosesia, , Italy

Site Status

ASST Spedali Civili

Brescia, , Italy

Site Status

Spedali Civili di Brescia Presidio Montichiari

Brescia, , Italy

Site Status

Policlinico Universitario di Monserrato - AOU Cagliari

Cagliari, , Italy

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Santissima Trinità

Cagliari, , Italy

Site Status

Aslto5 Piemonte

Chieri, , Italy

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Bassini

Cinisello Balsamo, , Italy

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U.O. Chirurgia Cles

Cles, , Italy

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Santa Maria dei Battuti

Conegliano, , Italy

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Aso Santa Croce E Carle Di Cuneo

Cuneo, , Italy

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Regina Montis Regalis Mondovì

Cuneo, , Italy

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Ospedale "E. Profili" Fabriano

Fabriano, , Italy

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Arcispedale Sant'Anna Ferrara

Ferrara, , Italy

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Istituto di chirurgia generale 1

Ferrara, , Italy

Site Status

Ospedale di Fidenza; AUSL Parma

Fidenza, , Italy

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AOU Careggi

Florence, , Italy

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Azienda Ospedaliera Universitaria Careggi

Florence, , Italy

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Chirurgia d' Urgenza Careggi

Florence, , Italy

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Ospedali Riuniti di Foggia

Foggia, , Italy

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Ospedale Morgagni-Pierantoni

Forlì, , Italy

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Ospedale Policlinico San Martino

Genova, , Italy

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Chirurgia Gorizia

Gorizia, , Italy

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Gualdo Tadino

Gubbio, , Italy

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Carlo Urbani, Jesi,

Iesi, , Italy

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Ospedale Sant'Andrea

La Spezia, , Italy

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Ospedale Del Delta

Lagosanto, , Italy

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N.S. della Mercede

Lanusei, , Italy

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ICOT

Latina, , Italy

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AAS 2 "Bassa Friulana-Isontina", Ospedale di Latisana-Palmanova

Latisana, , Italy

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Ospedale Civile San Salvatore

L’Aquila, , Italy

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Policlinico G. Martino

Messina, , Italy

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"ASST NORD MILANO Ospedale Città di Sesto San Giovanni "

Milan, , Italy

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"ASST OVEST MILANESE - Ospedale G. Fornaroli Magenta "

Milan, , Italy

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ASST Grande Ospedale Metropolitano Niguarda

Milan, , Italy

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IEO (Istituto Europeo di Oncologia)

Milan, , Italy

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IRCCS Policlinico Ospedale Maggiore Milano

Milan, , Italy

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Ospedale Sacco

Milan, , Italy

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San Paolo

Milan, , Italy

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San Raffaele

Milan, , Italy

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OCSAE

Modena, , Italy

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Policlinico di Modena

Modena, , Italy

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San Valentino

Montebelluna, , Italy

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A.O.U. Federico II

Napoli, , Italy

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Int Pascale Napoli

Napoli, , Italy

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Monaldi, AORN

Napoli, , Italy

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San Francesco

Nuoro, , Italy

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Giovanni Paolo II

Olbia, , Italy

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San Luigi Gonzaga

Orbassano, , Italy

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Aoup P. Giaccone

Palermo, , Italy

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Città di Castello

Perugia, , Italy

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Ospedale Santa Maria della Misericordia

Perugia, , Italy

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Ospedale civile

Pescara, , Italy

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Pederzoli

Peschiera del Garda, , Italy

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Ospedale Santa Corona

Pietra Ligure, , Italy

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Ospedale San Jacopo

Pistoia, , Italy

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Azienda Ospedaliera S. Maria degli Angeli

Pordenone, , Italy

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Ospedale San Tommaso dei Battuti- ULSS 4 Veneto orientale

Portogruaro, , Italy

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Santa Maria delle Croci

Ravenna, , Italy

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Chirurgia Generale

Riccione, , Italy

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Infermi

Rimini, , Italy

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Azienda Ospedaliera Sant'Andrea

Roma, , Italy

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Azienda Ospedaliera Universitaria Policlinico "Umberto I"

Roma, , Italy

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Ospedale San Camillo - Forlanini

Roma, , Italy

Site Status

ospedale San Filippo Neri Roma

Roma, , Italy

Site Status

Sant'Eugenio- Asl Roma2

Roma, , Italy

Site Status

Azienda Ospedaliera Universitaria " San Giovanni di Dio e Ruggi d'Aragona" - Università di Salerno

Salerno, , Italy

Site Status

Ospedale Nostra Signora di Bonaria

San Gavino Monreale, , Italy

Site Status

"A.O.U. Sassari "

Sassari, , Italy

Site Status

Ospedale Sassuolo SPA

Sassuolo, , Italy

Site Status

Policlinico Le Scotte

Siena, , Italy

Site Status

S. Vincenzo

Taormina, , Italy

Site Status

Citta della Salute e della Scienza di Torino sede Molinette

Torino, , Italy

Site Status

Cardinale Panico

Tricase, , Italy

Site Status

Azienda Sanitaria Universitaria Integrata di Trieste - Ospedale di Cattinara

Trieste, , Italy

Site Status

Ospedale Santa Maria della Misericordia

Udine, , Italy

Site Status

Sant'Andrea

Vercelli, , Italy

Site Status

Countries

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Italy

References

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Anania G, Agresta F, Artioli E, Rubino S, Resta G, Vettoretto N, Petz WL, Bergamini C, Arezzo A, Valpiani G, Morotti C, Silecchia G; SICE CoDIG (Colon Dx Italian Group). Laparoscopic right hemicolectomy: the SICE (Societa Italiana di Chirurgia Endoscopica e Nuove Tecnologie) network prospective trial on 1225 cases comparing intra corporeal versus extra corporeal ileo-colic side-to-side anastomosis. Surg Endosc. 2020 Nov;34(11):4788-4800. doi: 10.1007/s00464-019-07255-2. Epub 2019 Nov 18.

Reference Type DERIVED
PMID: 31741153 (View on PubMed)

Other Identifiers

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170595

Identifier Type: -

Identifier Source: org_study_id

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