Carbohydrate Oxidation in Elite Wheelchair Racers During Marathon Simulation
NCT ID: NCT04145050
Last Updated: 2021-04-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
12 participants
INTERVENTIONAL
2022-12-01
2024-07-01
Brief Summary
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Detailed Description
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Metabolic and physiological functions are altered in individuals with physical disabilities, so it is unknown how transferable these recommendations are to para athletes. As such, it is important to understand this population's unique carbohydrate requirements for performance optimization.
Recently, our group showed stable elevated circulating glucose concentrations by utilizing two different sources of CHO dosed at 60 g/h when compared to water. Significantly improved performance was observed with both CHO conditions. These findings, combined with studies showing decreased net muscle glycogen degradation during intravenous glucose infusion (3.5 g/min), show the importance of plasma glucose concentration for sustained performance. Therefore, the purpose of this study is to investigate the SCI-specific responses to exogenous CHO during a full marathon simulation (MS).
Twelve highly trained men and women (20-50 yrs old) will be recruited to the study. The inclusion criteria are: 1.) Best marathon time lower than 2h 2.) and ≥6 months of prior training history. After initial screenings, participants will perform three marathon (MS) trials. In cross-over trials, each subject will participate in a MS trial consisting of a challenge (90% of subject's best marathon time) followed by a time trial (TT) representing the last 10% of the marathon time. During each MS trial, participants will be randomly assigned to receive either water, 30g, or 60g of carbohydrate (CHO) every 15 minutes in the form of a sports nutrition beverage. Repeated blood and breath sampling will occur throughout the MS. These samples will be used to determine glucose concentration, lactate concentration, as well as CHO and fat oxidation. Heart rate, core temperature, blood pressure, ratings of perceived exertion and GI symptoms will also be assessed throughout the MS and after the time trial.
Completion of this research study will help to identify more appropriate CHO recommendations for para athletes to support prolonged endurance exercise. This will aid in the understanding of the unique physiological and metabolic needs of para athletes as compared to their able-bodied counterparts, thus enhancing inclusivity within sports nutrition literature.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Study Groups
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Carbohydrate Dose: 0 grams carbohydrate
Participants will be randomly selected, in a cross-over fashion, to ingest 0 grams/hour, 30 grams/ hour, or 60 grams/ hour of carbohydrate beverage throughout each experimental trial.
Carbohydrate dosing
The purpose of this study is to examine effects of different carbohydrate doses during marathon simulation in elite wheelchair racers.
Carbohydrate Dose: 30 grams carbohydrate
Participants will be randomly selected, in a cross-over fashion, to ingest 0 grams/hour, 30 grams/ hour, or 60 grams/ hour of carbohydrate beverage throughout each experimental trial.
Carbohydrate dosing
The purpose of this study is to examine effects of different carbohydrate doses during marathon simulation in elite wheelchair racers.
Carbohydrate Dose: 60 grams carbohydrate
Participants will be randomly selected, in a cross-over fashion, to ingest 0 grams/hour, 30 grams/ hour, or 60 grams/ hour of carbohydrate beverage throughout each experimental trial.
Carbohydrate dosing
The purpose of this study is to examine effects of different carbohydrate doses during marathon simulation in elite wheelchair racers.
Interventions
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Carbohydrate dosing
The purpose of this study is to examine effects of different carbohydrate doses during marathon simulation in elite wheelchair racers.
Eligibility Criteria
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Inclusion Criteria
* 6 months prior training history
Exclusion Criteria
* Active cardiovascular disease
* Diabetes Mellitus or other metabolic disorders
* Liver kidney, or urinary disease
* Musculoskeletal/Orthopedic disorders (e.g., osteoarthritis, rheumatoid arthritis, tendinitis, gout, fibromyalgia, patellar tendinopathy, or chronic low back pain)
* Neuromuscular disorders
* hypertension
* Diagnosed GI tract diseases
* Heart Disease
* Neurological disease
* Epilepsy
* Respiratory disease
* Pregnancy
* Contraindications for exercise
* \<6 months of prior training history
20 Years
50 Years
ALL
Yes
Sponsors
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University of Illinois at Urbana-Champaign
OTHER
Responsible Party
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Nicholas Burd
Primary Investigator
Principal Investigators
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Nicholas A Burd, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Illinois at Urbana-Champaign
Locations
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Disability Rehababilitation and Education Services
Champaign, Illinois, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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20020
Identifier Type: -
Identifier Source: org_study_id
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