Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2018-02-28
2018-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
PREVENTION
NONE
Study Groups
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Seated control (CON)
Participants remain seated in their habitual wheel chair for \~45 min (duration of exercise performed in other arms). Following the intervention they are fed.
Seated control (CON)
Seated rest
Liquid Meal
A liquid meal consisting of 600 kcal comprised of 50% carbohydrate, 35% fat, and 15% protein (by kcal).
Circuit resistance training (CRT)
Participants complete upper extremity resistance maneuvers (lifts) interspersed with low-load/high-speed arm cycling for a combined 30 repetitions of 6 lifts and \~20 min of arm cycling. During this time energy expenditure is measured via open-circuit indirect calorimetry. Following the intervention they are fed.
Circuit resistance training (CRT)
Alternating between six upper extremity resistance maneuvers interspersed with low-resistance/high-speed arm cycling.
Liquid Meal
A liquid meal consisting of 600 kcal comprised of 50% carbohydrate, 35% fat, and 15% protein (by kcal).
Moderate intensity continuous (MICT)
Participants complete continous arm cycling at a steady-state power output (intensity) matched to the energy expenditure (kcal/min) and duration of exercise (min) response during CRT. Following the intervention they are fed.
Moderate intensity continuous (MICT)
Arm cycling at a continuous power output
Liquid Meal
A liquid meal consisting of 600 kcal comprised of 50% carbohydrate, 35% fat, and 15% protein (by kcal).
High intensity interval training (HIIT)
Participants complete interval arm cycling at power output that varies between 2 min "active" and two min "recovery" periods. This interval exercise is matched to the total energy expenditure (accumulated kcals) response during CRT. Following the intervention they are fed.
High intensity interval training (HIIT)
Arm cycling at power outputs that vary between high and low intensity intervals
Liquid Meal
A liquid meal consisting of 600 kcal comprised of 50% carbohydrate, 35% fat, and 15% protein (by kcal).
Interventions
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Seated control (CON)
Seated rest
Moderate intensity continuous (MICT)
Arm cycling at a continuous power output
High intensity interval training (HIIT)
Arm cycling at power outputs that vary between high and low intensity intervals
Circuit resistance training (CRT)
Alternating between six upper extremity resistance maneuvers interspersed with low-resistance/high-speed arm cycling.
Liquid Meal
A liquid meal consisting of 600 kcal comprised of 50% carbohydrate, 35% fat, and 15% protein (by kcal).
Eligibility Criteria
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Inclusion Criteria
* Neurologically stable chronic (\>/= 1year) spinal cord injury (SCI)
* American Spinal Injury Association Impairment Scale (AIS) grade A, B, or C
* SCI at level \</= the first thoracic vertebrae (T1)
Exclusion Criteria
* Contraindication to exercise (ACSM Guideline, 10th edition)
* Lower extremity fracture or dislocation within 6 months of participation,
* History head injury or seizures.
* Inability to consent.
* Restrictions in upper extremity range of motion that would prevent an individual from achieving an unhindered arm cycling motion or moving throughout a range needed to perform resistance maneuvers.
* A pressure ulcer at ischial/gluteus, trochanteric, sacral, or heel sites within the last 3 months.
* Pregnancy determined by urine testing in sexually active females.
* Imprisonment in state or federal jail or prison.
18 Years
ALL
Yes
Sponsors
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University of Miami
OTHER
Responsible Party
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Mark S. Nash, Ph.D., FACSM
Professor
Principal Investigators
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Mark S Nash, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University of Miami
Locations
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Lois Pope Life Center
Miami, Florida, United States
Countries
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References
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McMillan DW, Maher JL, Jacobs KA, Mendez AJ, Nash MS, Bilzon JLJ. Effects of Exercise Mode on Postprandial Metabolism in Humans with Chronic Paraplegia. Med Sci Sports Exerc. 2021 Jul 1;53(7):1495-1504. doi: 10.1249/MSS.0000000000002593.
McMillan DW, Maher JL, Jacobs KA, Mendez AJ, Nash MS, Bilzon JLJ. Influence of upper-body continuous, resistance or high-intensity interval training (CRIT) on postprandial responses in persons with spinal cord injury: study protocol for a randomised controlled trial. Trials. 2019 Aug 13;20(1):497. doi: 10.1186/s13063-019-3583-1.
Other Identifiers
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20171114
Identifier Type: -
Identifier Source: org_study_id
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