Blood Flow-restricted Resistance Exercise to Promote Muscle Strength and Use in Adults With Incomplete Spinal Cord Injury

NCT ID: NCT06907381

Last Updated: 2025-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-04-01

Study Completion Date

2026-02-15

Brief Summary

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Recovery of arm and hand motor control is critical for independence and quality of life following incomplete spinal cord injury (iSCI). Blood flow-restricted resistance exercise (BFRE) has emerged as a potential treatment addressing this need, but treatment guidelines and research reporting effectiveness are sparse. The purpose of this work is to provide case reports of people with cervical iSCI who use BFRE supplemented by electrical stimulation (ES) to increase the strength and functional use of selected upper extremity muscles.

Detailed Description

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Conditions

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Spinal Cord Injury Cervical

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Blood flow-restricted resistance exercise

Participants will engage in baseline measurement of blood pressure, strength of target muscle contractions, and level of support needed for functional task performance. They will then begin BFRE treatment supplemented by electrical stimulation, if needed, two times weekly. Each exercise session will include performance of four sets of 20 repetitions of target muscle contraction on each side of the body followed by functional task performance.

Intervention Type BEHAVIORAL

Other Intervention Names

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BFRE

Eligibility Criteria

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Inclusion Criteria

* Incomplete cervical spinal cord injury
* Resting blood pressure between 80/50 mmHg and 150/90 mmHg for at least three consecutive days
* Native speaker of English

Exclusion Criteria

* Recent history of deep vein thrombosis or cardiovascular disease including uncontrolled hypertension or a blood-clotting disorder
* Routine experience of orthostatic hypotension as defined as a drop in systolic/diastolic blood pressure greater than 20/10 mmHg when engaging in physical activity
* Severe cognitive, communication, or behavioral disorder as determined by treatment team
Minimum Eligible Age

19 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Quality Living, Inc.

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sara Waid, DPT

Role: PRINCIPAL_INVESTIGATOR

Quality Living, Inc.

Locations

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Quality Living, Inc.

Omaha, Nebraska, United States

Site Status

Countries

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United States

Other Identifiers

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QualityLiving

Identifier Type: -

Identifier Source: org_study_id

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