Restoring Hand Function Utilizing Nerve Transfers in Persons With Cervical Spinal Cord Injuries
NCT ID: NCT03451474
Last Updated: 2021-10-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
3 participants
INTERVENTIONAL
2018-04-01
2020-07-17
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Upper extremity nerve transfer surgery
Upper extremity nerve transfer surgery is a surgical procedure where axons from an intact, functioning upper extremity peripheral nerve are moved to a target muscle that demonstrates significant weakness or paralysis as a result of spinal cord injury. After allowing time for recovery from surgery and for nerve growth to occur, the patient undergoes hand/occupational therapy in order to retrain motor skills.
Upper extremity nerve transfer surgery
Upper extremity nerve transfer surgery is a surgical procedure where axons from an intact, functioning upper extremity peripheral nerve are moved to a target muscle that demonstrates significant weakness or paralysis as a result of spinal cord injury. After allowing time for recovery from surgery and for nerve growth to occur, the patient undergoes hand/occupational therapy in order to retrain motor skills.
Interventions
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Upper extremity nerve transfer surgery
Upper extremity nerve transfer surgery is a surgical procedure where axons from an intact, functioning upper extremity peripheral nerve are moved to a target muscle that demonstrates significant weakness or paralysis as a result of spinal cord injury. After allowing time for recovery from surgery and for nerve growth to occur, the patient undergoes hand/occupational therapy in order to retrain motor skills.
Eligibility Criteria
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Inclusion Criteria
* \>6 months post-injury
* International Classification of Surgery of the Hand in Tetraplegia (ICSHT) category 0-4
* Cervical spinal cord injury resulting in arm \& hand functional impairment, with at least preserved elbow flexion
* Physically and mentally willing and able to comply with study protocol
* Lives in the immediate area and has no plans to relocate
* Provides informed consent and HIPAA release of medical information
Exclusion Criteria
* Any return or ongoing clinical recovery of distal motor function within 6 months after injury
* Physically/mentally compromised
* Systemic disease that would affect the patient's welfare or the research study
* Immunologically suppressed or immunocompromised
* Currently undergoing long-term steroid therapy
* Active malignancy
* Pending litigation or receiving Workers Compensation related to injury or accident
* Pregnancy
* Significant contractures and/or limitations in passive range of motion in the arm or hand
* Poorly controlled upper extremity spasticity
* Uncontrolled pain or hypersensitivity
* Previous or current injury preventing use of tendon transfers to restore upper extremity function
* History of brachial plexus injury or systemic neuropathic process
* In the opinion of the Principal Investigator the subject would not be a candidate for the procedure
18 Years
65 Years
ALL
No
Sponsors
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The University of Texas Health Science Center, Houston
OTHER
Responsible Party
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Principal Investigators
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Wesley H Jones, MD
Role: PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center, Houston
Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, United States
Countries
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Other Identifiers
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HSC-MS-17-0081
Identifier Type: -
Identifier Source: org_study_id