The Effect of Locomotor Training on Children With Incomplete Spinal Cord Injuries

NCT ID: NCT00931983

Last Updated: 2011-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2009-03-31

Brief Summary

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--Participation open to all Canadian residents--

The purpose of this study is to address how well children with incomplete spinal cord injuries of greater than 12 months duration who remain non-functional ambulators improve through body weight assisted treadmill training (BWATT).

Detailed Description

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In the past, this type of treatment has been offered to adults living with a spinal cord injury, but only recently has it been extended, in the US, to children so affected. Numerous trials indicate that BWSTT does improve human gait patterns in adults. As children have more neuroplasticity than adults, we believe they should respond well to BWSTT.

The BWSTT uses a counterweight harness system to unload the patient's body weight while he or she is on a treadmill. The patient's legs are manually moved by trained therapists through the human gait cycle while maintaining a correct upright posture. Functional and social re-integration outcome assessments are administered before and after each treatment period.

The aim, this year, is to recruit five children who have been living with a spinal cord injury for at least 12 months. The 12-month timeframe was chosen to limit any gait improvement from spontaneous recovery as well as to ensure medical stability.

The study will be conducted over a nine-week period. There are two three-week training sessions separated by a three-week rest period. The BWSTT therapy will be held twice daily for 30 minute sessions. The children and their families return home between the two training periods and are allowed to continue any conventional physiotherapy program they started prior to participating in the study. Outcomes will be re-evaluated during the second three-week training period.

Conditions

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Spinal Cord Injuries

Keywords

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Incomplete spinal cord injuries Walking Treadmill Training

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Children between the ages of 4-18 with incomplete ASIA C or D spinal cord injuries at least 12 months before study enrolment
* Non-ambulatory or 'exercise only' ambulators with or without assistive devices
* Normal motor and cognitive development up to time of injury
* Medical Stability

Exclusion Criteria

* Other neuromuscular disease
* Contraindication to weight bearing on lower extremities
* Pressure sores where harness would be applied
* Uncontrollable hypotension when upright
* Lower limb contractures impeding range of motion necessary for ambulation
* Prior enrolment in a BWATT program
* Unable to commit to intervention for duration of protocol
Minimum Eligible Age

4 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rick Hansen Foundation

OTHER

Sponsor Role collaborator

Shriners Hospitals for Children

OTHER

Sponsor Role collaborator

Fondation pour la Recherche sur la Moelle Épinière (Spinal Cord Research Foundation)

UNKNOWN

Sponsor Role collaborator

McGill University

OTHER

Sponsor Role lead

Responsible Party

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Shriners Hospitals for Children-Canada

Principal Investigators

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Mohan Radhakrishna, Md, FRCPC

Role: PRINCIPAL_INVESTIGATOR

McGill University, Shriners Hospitals for Children-Canada

Hugues Barbeau, Pt, PhD

Role: STUDY_CHAIR

McGill University

Joanne Ruck-Gibis, Pt, MSc

Role: STUDY_CHAIR

McGill University

Kathleen Montpetit, Ot, MSc

Role: STUDY_CHAIR

McGill University, Shriners Hospitals for Children-Canada

Jean Ouellet, Md, FRCSC

Role: STUDY_CHAIR

McGill University, Shriners Hospitals for Children-Canada

Locations

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Shriners Hospitals for Children-Canada

Montreal, Quebec, Canada

Site Status

Countries

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Canada

References

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Barbeau H, Nadeau S, Garneau C. Physical determinants, emerging concepts, and training approaches in gait of individuals with spinal cord injury. J Neurotrauma. 2006 Mar-Apr;23(3-4):571-85. doi: 10.1089/neu.2006.23.571.

Reference Type BACKGROUND
PMID: 16629638 (View on PubMed)

Behrman AL, Nair PM, Bowden MG, Dauser RC, Herget BR, Martin JB, Phadke CP, Reier PJ, Senesac CR, Thompson FJ, Howland DR. Locomotor training restores walking in a nonambulatory child with chronic, severe, incomplete cervical spinal cord injury. Phys Ther. 2008 May;88(5):580-90. doi: 10.2522/ptj.20070315. Epub 2008 Mar 6.

Reference Type BACKGROUND
PMID: 18326054 (View on PubMed)

Other Identifiers

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2009-38

Identifier Type: -

Identifier Source: org_study_id