Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE1
20 participants
INTERVENTIONAL
2019-08-01
2020-01-05
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Exogenous Ketones and Glucose Tolerance
NCT03461068
The Effect of Different Ketone Supplements on β-OHB and Blood Glucose in Healthy Individuals
NCT05273411
Metabolomic Signature of Exogenous Ketosis
NCT05699707
Ketone Supplementation, Glucose Control, and Cardiovascular Function
NCT03817749
Effects of Exogenous Ketones in Healthy Young Adults
NCT03452761
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Ketone monoester
Acute morning dose of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate (0.45 ml/kg body weight)
Ketone monoester
Acute ingestion of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate prior a 2-hour high carbohydrate mixed meal tolerance test.
Placebo
Acute morning dose of flavour-matched placebo.
Placebo
Acute ingestion of a taste-matched placebo prior a 2-hour high carbohydrate mixed meal tolerance test.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Ketone monoester
Acute ingestion of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate prior a 2-hour high carbohydrate mixed meal tolerance test.
Placebo
Acute ingestion of a taste-matched placebo prior a 2-hour high carbohydrate mixed meal tolerance test.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Not taking any medications affecting glucose metabolism
Exclusion Criteria
* Diagnosed with the chronic medical condition that may impact consumption of carbohydrates or supplements (e.g., diabetes, heart disease)
* Are currently using medications that may interfere with insulin sensitivity
* Adhere to a strict high-fat low-carbohydrate or ketogenic diet (within the last 3 months)
* Are currently using ketone supplements
* Unable to travel to and from the university in order to make your testing appointments.
* Unable to follow the controlled diet instructions required for the study.
* If pregnant or are planning to become pregnant during the study (if female)
18 Years
35 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of British Columbia
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Jonathan Little
Associate Professor
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of British Columbia, Okanagan
Kelowna, British Columbia, Canada
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
H16-01846-B
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.