Laser Therapy on Orthodontic Tooth Movement

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-01

Study Completion Date

2019-09-16

Brief Summary

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The aims of this study will be to evaluate if a Lower Level Laser Therapy (LLLT): (1) enhances the levels of important pro-inflammatory chemokines involved in the bone remodeling process; (2) increases the rate of orthodontic tooth movement (OTM) on human subjects.

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Detailed Description

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Conditions

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Laser Therapy Orthodontic Tooth Movement Bone Remodeling

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Low-level laser therapy and no orthodontic force

No orthodontic force. Laser is applied on the first day and the premolars is extracted after 24 hours

Group Type EXPERIMENTAL

Low-level Laser Therapy

Intervention Type DEVICE

Low-level laser therapy is applied on premolars that will be extracted for treatment plan reasons

Low-level laser therapy and application of orthodontic force

Orthodontic force and Laser is applied on the first day and the premolars is extracted after 24 hours

Group Type EXPERIMENTAL

Low-level Laser Therapy

Intervention Type DEVICE

Low-level laser therapy is applied on premolars that will be extracted for treatment plan reasons

Orthodontic force

Intervention Type PROCEDURE

Mechanical loading is applied on premolars that will be extracted for treatment plan reasons and in canines for tooth movement

Orthodontic force only

Orthodontic force is applied and the premolars is extracted after 24 hours, with no laser therapy

Group Type ACTIVE_COMPARATOR

Orthodontic force

Intervention Type PROCEDURE

Mechanical loading is applied on premolars that will be extracted for treatment plan reasons and in canines for tooth movement

Low-level laser therapy and orthodontic force

Orthodontic force and Laser is applied and the orthodontic tooth movement is evaluated

Group Type EXPERIMENTAL

Low-level Laser Therapy

Intervention Type DEVICE

Low-level laser therapy is applied on premolars that will be extracted for treatment plan reasons

Orthodontic force

Intervention Type PROCEDURE

Mechanical loading is applied on premolars that will be extracted for treatment plan reasons and in canines for tooth movement

Orthodontic force with no laser therapy

Orthodontic force is applied and the orthodontic tooth movement is evaluated, with no laser therapy

Group Type ACTIVE_COMPARATOR

Orthodontic force

Intervention Type PROCEDURE

Mechanical loading is applied on premolars that will be extracted for treatment plan reasons and in canines for tooth movement

Interventions

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Low-level Laser Therapy

Low-level laser therapy is applied on premolars that will be extracted for treatment plan reasons

Intervention Type DEVICE

Orthodontic force

Mechanical loading is applied on premolars that will be extracted for treatment plan reasons and in canines for tooth movement

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Facial convexity
* Protrusion or biprotrusion of the incisors
* Dental crowding
* Healthy periodontal condition
* Satisfactory oral hygiene

Exclusion Criteria

* Patients under medications that may interfere with bone metabolism, such as anti-inflammatory, antibiotics and hormonal supplements in the previous three months
* Skeletal crossbite
* Parafunctional habits
* Occlusal interference

Minimum Eligible Age

13 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes