Effect of Low Level Laser Therapy in Accelerating Tooth Movement For Dental Crowding Cases

NCT ID: NCT02568436

Last Updated: 2016-07-11

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 26 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2015-07-31
• Study Completion Date: 2016-05-31

Brief Summary

26 participants from the Orthodontic Department at University of Damascus Dental School will be randomly assigned into two groups. In the experimental group, a low level laser with a wave length of 830 nm, output of 150 mw, energy of 2 j per point and application time of 15 seconds per point will be applied on each tooth of the six upper incisors according to this protocol: the root will be divided into 2 halves; gingival and cervical. Laser will be applied in the center of each half from both the buccal and palatal sides which means 4 application points and a total energy of 8 j per each tooth. Control group will undergo typical orthodontic treatment with the laser device applied the same manner but without being turned on (to get the placebo effect for pain reduction effect). This procedure will be repeated after 3, 7, 14 days and each 15 days from the beginning of the second month till the end of the leveling and alignment stage.

Detailed Description

The long time needed for orthodontic treatment is considered one of the biggest obstacles which make patients refuse to undergo treatment. It also has many disadvantages including higher caries rates, gingivitis, and root resorption. It also combined commonly with pain, which reducing patient acceptance and cooperation with treatment.

Low level laser therapy in orthodontic has shown pain-reducing effects with an effect in biomodulation which lead to increased orthodontic tooth movement rate and reducing risk of root resorption.

A recent systematic review states that low level laser therapy has shown efficiency in accelerating orthodontic tooth movement, but there is a need for more studies to determine the best protocols regarding energy and frequency. A review of the literature shows that there is no randomized controlled trails evaluating its efficiency in accelerating orthodontic tooth movement in regard of dental crowding cases, which is the main purpose of this study.

Conditions

Maxillary Crowded Teeth

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Conventional Decrowding

Crowded upper incisors will be treated in the conventional manner with a fake irradiation without using low level laser therapy.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Low Level Laser Therapy

Each maxillary incisor will be subjected to low level laser therapy at specific times in order to accelerate tooth movement

Group Type: EXPERIMENTAL

low level laser therapy

Intervention Type: RADIATION

low level laser therapy is intended to accelerate tooth movement

Interventions

low level laser therapy

low level laser therapy is intended to accelerate tooth movement

Intervention Type: RADIATION

Eligibility Criteria

Inclusion Criteria

1. Patients aged between (16 - 24) years.

2. Moderate crowding (3 - 5) mm in the anterior region of the maxillary dental arch with an irregularity index of (7 mm or more) mm according to Little Index with an indication to extract upper two premolars.

3. All upper teeth are existed (except for third molars).

4. Patients have not undergone previous orthodontic treatment.

5. Patients have not undergone any medical treatment that interfere with orthodontic tooth movement (Cortisone, NSAIDs, …).

6. Patient with good oral hygiene (Plaque Index less than 1).

Exclusion Criteria

1. Any medical condition affecting orthodontic tooth movement.

2. Bad oral hygiene (Plaque Index greater than 1).

3. Any peri-apical lesions developed during treatment.

4. Patient lack of commitment toward follow-up appointments.

• Minimum Eligible Age: 16 Years
• Maximum Eligible Age: 24 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Damascus University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Mohammad Moaffak Al-Sayed Hasan, DDS

Role: PRINCIPAL_INVESTIGATOR

MSc student at the Orthodontic Department, University of Damascus Dental School

Kinda Sultan, DDS MSc PhD

Role: STUDY_DIRECTOR

Senior Lecturer in Orthodontics, University of Damascus Dental School, SYRIA

Omar Hamadah, DDS MSc PhD

Role: STUDY_DIRECTOR

Senior Lecturer, Oral Medicine Department, University of Damascus Dental School, Damascus, Syria

Locations

Department of Orthodontics, University of Damascus Dental School

Damascus, Rif-dimashq Governorate, Syria

Countries

Syria

References

Cruz DR, Kohara EK, Ribeiro MS, Wetter NU. Effects of low-intensity laser therapy on the orthodontic movement velocity of human teeth: a preliminary study. Lasers Surg Med. 2004;35(2):117-20. doi: 10.1002/lsm.20076.

Reference Type: BACKGROUND

PMID: 15334614 (View on PubMed)

Doshi-Mehta G, Bhad-Patil WA. Efficacy of low-intensity laser therapy in reducing treatment time and orthodontic pain: a clinical investigation. Am J Orthod Dentofacial Orthop. 2012 Mar;141(3):289-297. doi: 10.1016/j.ajodo.2011.09.009.

Reference Type: BACKGROUND

PMID: 22381489 (View on PubMed)

Heravi F, Moradi A, Ahrari F. The effect of low level laser therapy on the rate of tooth movement and pain perception during canine retraction. Oral Health Dent Manag. 2014 Jun;13(2):183-8.

Reference Type: BACKGROUND

PMID: 24984620 (View on PubMed)

Kau CH, Kantarci A, Shaughnessy T, Vachiramon A, Santiwong P, de la Fuente A, Skrenes D, Ma D, Brawn P. Photobiomodulation accelerates orthodontic alignment in the early phase of treatment. Prog Orthod. 2013 Sep 19;14:30. doi: 10.1186/2196-1042-14-30.

Reference Type: BACKGROUND

PMID: 24326198 (View on PubMed)

Nobrega C, da Silva EM, de Macedo CR. Low-level laser therapy for treatment of pain associated with orthodontic elastomeric separator placement: a placebo-controlled randomized double-blind clinical trial. Photomed Laser Surg. 2013 Jan;31(1):10-6. doi: 10.1089/pho.2012.3338. Epub 2012 Nov 15.

Reference Type: BACKGROUND

PMID: 23153291 (View on PubMed)

Tortamano A, Lenzi DC, Haddad AC, Bottino MC, Dominguez GC, Vigorito JW. Low-level laser therapy for pain caused by placement of the first orthodontic archwire: a randomized clinical trial. Am J Orthod Dentofacial Orthop. 2009 Nov;136(5):662-7. doi: 10.1016/j.ajodo.2008.06.028.

Reference Type: BACKGROUND

PMID: 19892282 (View on PubMed)

AlSayed Hasan MMA, Sultan K, Ajaj M, Voborna I, Hamadah O. Low-level laser therapy effectiveness in reducing initial orthodontic archwire placement pain in premolars extraction cases: a single-blind, placebo-controlled, randomized clinical trial. BMC Oral Health. 2020 Jul 20;20(1):209. doi: 10.1186/s12903-020-01191-7.

Reference Type: DERIVED

PMID: 32690001 (View on PubMed)

Other Identifiers

UDDS-Ortho-02-2015

Identifier Type: -

Identifier Source: org_study_id