Acceleration of Alignment of Crowded Lower Anterior Teeth

NCT ID: NCT03659097

Last Updated: 2021-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-02

Study Completion Date

2021-06-20

Brief Summary

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Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be included. Then, initial diagnostic records (diagnostic gypsum models, internal and external oral photographs, as well as radiographic images) will be studied to ensure that the selection criteria are accurately matched.

The aim of this study is to compare two groups of patients with moderate crowding of the lower anterior teeth First group (Experimental): the patients in this group will be treated with orthodontic fixed appliances + surgery to the alveolus of the lower anterior teeth in order to induce remodeling of the bony structures and enhance orthodontic movement.

Second group (Control): the patients in this group will be treated using fixed appliances with any acceleration method.

Detailed Description

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Conditions

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Malocclusion, Angle Class I Crowded Teeth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Periodontally accelerated osteogenic orthodontics

Patients in this group will undergo orthodontic treatment plus periodontally accelerated osteogenic orthodontics in order to induce tooth movement.

Group Type EXPERIMENTAL

periodontally accelerated osteogenic orthodontics

Intervention Type PROCEDURE

Surgery will be performed to the lower anterior bony segment of the lower jaw in order to accelerate tooth movement

Traditional orthodontics

Patients in this group will undergo traditional orthodontics without any surgical interventions

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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periodontally accelerated osteogenic orthodontics

Surgery will be performed to the lower anterior bony segment of the lower jaw in order to accelerate tooth movement

Intervention Type PROCEDURE

Other Intervention Names

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PAOO

Eligibility Criteria

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Inclusion Criteria

* Class I malocclusion with moderate crowding (4-6 mm of tooth-size-arch-length-discrepancy).
* Good oral hygiene and periodontal health.
* No severe skeletal discrepancy.
* Normal inclination for the upper and lower incisors.
* No congenitally missing or extracted teeth (except for the third molars).

Exclusion Criteria

* Bi-maxillary severe dental protrusion.
* Previous orthodontic treatment.
* Subject with psychological abnormalities.
* Subject with systemic diseases.
Minimum Eligible Age

18 Years

Maximum Eligible Age

28 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Damascus University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hallaj I Alsino, DDS

Role: PRINCIPAL_INVESTIGATOR

MSc student at the Orthodontic Department, University of Damascus Dental School, Damascus, Syria

Mohammad Y Hajeer, DDS MSc PhD

Role: STUDY_DIRECTOR

Associate Professor of Orthodontics, University of Damascus Dental School, Damascus, Syria

Issam Khoury, DDS MSc PhD

Role: STUDY_DIRECTOR

Professor of Oral and Maxillofacial Surgery, Oral and Maxillofacial Surgery Department, University of Damascus Dental School, Damascus, SYRIA

Locations

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Department of Orthodontics, University of Damascus Dental School

Damascus, , Syria

Site Status

Countries

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Syria

References

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Munoz F, Jimenez C, Espinoza D, Vervelle A, Beugnet J, Haidar Z. Use of leukocyte and platelet-rich fibrin (L-PRF) in periodontally accelerated osteogenic orthodontics (PAOO): Clinical effects on edema and pain. J Clin Exp Dent. 2016 Apr 1;8(2):e119-24. doi: 10.4317/jced.52760. eCollection 2016 Apr.

Reference Type BACKGROUND
PMID: 27034749 (View on PubMed)

Bahammam MA. Effectiveness of bovine-derived xenograft versus bioactive glass with periodontally accelerated osteogenic orthodontics in adults: a randomized, controlled clinical trial. BMC Oral Health. 2016 Nov 30;16(1):126. doi: 10.1186/s12903-016-0321-x.

Reference Type BACKGROUND
PMID: 27903250 (View on PubMed)

Yu H, Jiao F, Wang B, Shen SG. Piezoelectric decortication applied in periodontally accelerated osteogenic orthodontics. J Craniofac Surg. 2013;24(5):1750-2. doi: 10.1097/SCS.0b013e3182902c5a.

Reference Type BACKGROUND
PMID: 24036771 (View on PubMed)

Nowzari H, Yorita FK, Chang HC. Periodontally accelerated osteogenic orthodontics combined with autogenous bone grafting. Compend Contin Educ Dent. 2008 May;29(4):200-6; quiz 207, 218.

Reference Type BACKGROUND
PMID: 18533317 (View on PubMed)

Amit G, Jps K, Pankaj B, Suchinder S, Parul B. Periodontally accelerated osteogenic orthodontics (PAOO) - a review. J Clin Exp Dent. 2012 Dec 1;4(5):e292-6. doi: 10.4317/jced.50822. eCollection 2012 Dec 1.

Reference Type BACKGROUND
PMID: 24455038 (View on PubMed)

Other Identifiers

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UDDS-Ortho-17-2018

Identifier Type: -

Identifier Source: org_study_id

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