The Effects of Exercise Program in Alzheimer's Patients With Mild to Moderate Stage Alzheimer's Disease

NCT ID: NCT04021888

Last Updated: 2019-07-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-16

Study Completion Date

2020-07-30

Brief Summary

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The primary aim of this trial is to investigate the feasibility of an exercise program consisting of respiratory exercises, aerobic exercises and strengthening exercises in mild to moderate Alzheimer's disease. The trial also aims to investigate the effectiveness of the exercise program on respiratory symptoms, exercise capacity, cognition, physical performance, depression, sleepiness, activities of daily living and quality of life.

Patients will be divided into exercise (intervention) and control group by randomization method. The study is planned to be performed with a total of 60 patients, 30 in each group. The patients in the exercise group will be given breathing exercises aerobic exercises and strengthening exercises for 2 days a week for 12 weeks, about 30-40 minutes while the patients in the control group will be provided with suggestions, home exercise program and daily life activities

Detailed Description

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Exercise group was trained 3 times a week under the supervision of a physiotherapist and encouraged to exercise at home on other days

Conditions

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Alzheimer Disease Aerobic Exercise Breathing Exercise Resistance Training

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
An assessor who was blinded to treatment groups assessed clinical outcomes before the treatment process. The same assessor was also repeated assessments at 13th week (at the end of treatment process)

Study Groups

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Exercise Group

Group Type EXPERIMENTAL

Exercise

Intervention Type OTHER

Education of patients and their caregivers, deep breathing exercise, aerobic exercise and resistance training with elastic bands

Control

Group Type ACTIVE_COMPARATOR

Exercise

Intervention Type OTHER

Education of patients and their caregivers, deep breathing exercise, aerobic exercise and resistance training with elastic bands

Interventions

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Exercise

Education of patients and their caregivers, deep breathing exercise, aerobic exercise and resistance training with elastic bands

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* aged over 65 years
* can walk independent

Exclusion Criteria

* can't see
* have done any exercise in the last 6 months
* have a major and uncontrolled orthopedic, neurological or cardiopulmonary problem that restricts functioning
* having non Alzheimer's disease dementia
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sevgi Ozalevli

UNKNOWN

Sponsor Role collaborator

Gorsev Yener

UNKNOWN

Sponsor Role collaborator

Dokuz Eylul University

OTHER

Sponsor Role lead

Responsible Party

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Elvan Keles

Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Elvan Keleş, PT, PhD

Role: PRINCIPAL_INVESTIGATOR

İzmir Katip Çelebi Üniversitesi

Locations

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Elvan Keleş

İzmi̇r, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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KELES

Identifier Type: -

Identifier Source: org_study_id

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