Exercise Capacity in COPD

NCT ID: NCT03889964

Last Updated: 2020-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-01

Study Completion Date

2020-12-31

Brief Summary

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In this study, cardiopulmonary exercise will be assessed to characterize the relevance of severity of COPD and coexisting cardiovascular comorbidities for exercise capacity.

Detailed Description

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In patients with chronic obstructive pulmonary disease (COPD) the interpretation of dyspnoea also needs to consider coexisting cardiovascular disease. Cardiopulmonary exercise testing (CPET) is used to characterize pulmonary and cardiac function and limitations during exercise. The investigators hypothesise that cardiopulmonary exercise is reduced in COPD patients with coexisting cardiovascular disease as well as in more symptomatic patients and in patients with frequent exacerbations. For this purpose, 100 patients with with stable COPD are characterized by clinical characteristics, laboratory tests, lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing.

Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with stable COPD

Measurement of lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing

Intervention Type OTHER

Measurement of lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing

Interventions

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Measurement of lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing

Measurement of lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients with stable chronic obstructive pulmonary disease, exacerbated or stable
* 40-80 years
* sinus rhythm
* informed written consent

Exclusion Criteria

* Inability to give written consent
* acute myocardial infarction with ST-segment elevations in last 30 days
* severe acute or chronic renal dysfunction
* severe heart failure-
* atrial fibrillation
* severe valve disease
* severe hypoxemia
* long term oxygen therapy or non invasive ventilation
Minimum Eligible Age

40 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Klinik für Kardiologie, Pneumologie und Angiologie

OTHER

Sponsor Role lead

Responsible Party

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Klinik für Kardiologie, Pneumologie und Angiologie

Principle Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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University Hospital Düsseldorf, Division of Cardiology, Pulmonary Disease and Vascular Medicine

Düsseldorf, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Stefanie Keymel, MD

Role: CONTACT

+492118118800

Rabea Wagstaff, M.A.

Role: CONTACT

Facility Contacts

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Stefanie Keymel, MD

Role: primary

Other Identifiers

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17-033

Identifier Type: -

Identifier Source: org_study_id

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