Effects of Rehabilitation on Muscle Fibre Composition and Capillaries in Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT ID: NCT01715337

Last Updated: 2014-04-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-02-28

Study Completion Date

2014-04-30

Brief Summary

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Pulmonary rehabilitation has been established as an evidence-based and recommended therapy in patients with chronic obstructive pulmonary disease (COPD). The aim of our study is to show a potential change in muscle fibre composition and in the amount of capillaries in quadriceps muscle from pre tob post 3-week rehabilitation. Pulmonary rehabilitation includes standardised exercise training, e.g. cycling and strength training for major muscle groups.

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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pulmonary rehabilitation

Group Type OTHER

pulmonary rehabilitation

Intervention Type OTHER

3-week rehabilitation including exercise training, breathing therapy, psychosocial support, medical treatment etc.

Interventions

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pulmonary rehabilitation

3-week rehabilitation including exercise training, breathing therapy, psychosocial support, medical treatment etc.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* chronic obstructive pulmonary disease
* FEV1%pred. \< 50%

Exclusion Criteria

* acute exacerbation
* exacerbation in the last 4 weeks
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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German Sport University, Cologne

OTHER

Sponsor Role collaborator

Schön Klinik Berchtesgadener Land

OTHER

Sponsor Role lead

Responsible Party

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Klaus Kenn

Head physician (department of pneumology)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Klaus Kenn, Dr. med.

Role: STUDY_CHAIR

Klinikum Berchtesgadener Land

Locations

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Schön Klinik Berchtesgadener Land

Schönau am Königssee, , Germany

Site Status

Countries

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Germany

Other Identifiers

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COPD muscle 2011

Identifier Type: -

Identifier Source: org_study_id

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