Alcohol Consumption and Type 2 Diabetes Mellitus Risk in Nonalcoholic Fatty Liver Disease

NCT ID: NCT03847116

Last Updated: 2019-07-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

14014 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-01

Study Completion Date

2019-02-10

Brief Summary

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This study explored the cross-sectional and prospective associations between light-to-moderate alcohol consumption (LMAC) and risk of type 2 diabetes mellitus (T2DM) in individuals with nonalcoholic fatty liver disease (NAFLD).

Detailed Description

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Conditions

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Nonalcoholic Fatty Liver Disease Light-to-moderate Alcohol Consumption Type2 Diabetes Mellitus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. aged 18 years or above
2. undergoing annual health examinations in 2009 in Zhenhai Lianhua Hospital, Ningbo, China.
3. informed about the study

Exclusion Criteria

1. female participants;
2. missing data on ultrasound, alcohol consumption, and T2DM status;
3. alcohol consumption \> 210 g per week, and binge drinkers;
4. with evidence of other liver diseases including viral hepatitis, autoimmune hepatitis, and drug-induced liver disease.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ningbo No. 1 Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Ningbo first hospital

Ningbo, Zhejiang, China

Site Status

Countries

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China

References

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Xu L, Xie J, Chen S, Chen Y, Yang H, Miao M, Zhu Z, Li Y, Yu C, Xu C. Light-to-Moderate Alcohol Consumption Is Associated With Increased Risk of Type 2 Diabetes in Individuals With Nonalcoholic Fatty Liver Disease: A Nine-Year Cohort Study. Am J Gastroenterol. 2020 Jun;115(6):876-884. doi: 10.14309/ajg.0000000000000607.

Reference Type DERIVED
PMID: 32282335 (View on PubMed)

Other Identifiers

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LHNAFLD 2018-V1.0

Identifier Type: -

Identifier Source: org_study_id

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