Evaluation of Kidney Graft's Fibrosis With Real Time Shear-wave Elastography
NCT ID: NCT03819400
Last Updated: 2024-04-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
45 participants
OBSERVATIONAL
2019-03-29
2022-05-16
Brief Summary
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Tissue's fibrosis is a proliferation of extracellular matrix, leading to an increase of fibrosed tissue rigidity.
Elastography is an ultrasound technique allowing evaluation of tissues' rigidity.
The purpose is the validation of elastograhpy, innovative and non -invasive technique, and more specifically Shear Wave Elastography (SWE). For this, strain ratio (SR) could improve intra-operator variability and estimate fibrosis' degree of kidney's graft.
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Detailed Description
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Tissue's fibrosis is a proliferation of extracellular matrix, leading to an increase of fibrosed tissue rigidity.
Elastography is an ultrasound technique allowing evaluation of tissues' rigidity.
The purpose is the validation of elastograhpy, innovative and non -invasive technique, and more specifically Shear Wave Elastography (SWE). For this, strain ratio (SR) could improve intra-operator variability and estimate fibrosis' degree of kidney's graft.
Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* More than 18 years-old
Exclusion Criteria
* Hydronephrosis / urinary obstacle
* Pathologies with an intrinsic compression on the graft
* Stenosis hemodynamically significant of graft artery (lengthening of Systolic Ascent Time \> 70 ms)
* Contra-indication to systematical punction-biopsy on Month 3 :
* Ischemia of post-transplanted graft
* Alive donor HLA identical
* Hemostasis disorder or unable to stop antiaggregant or anticoagulant
* Hydronephrosis / urinary obstacle
* Opposition to use the data
18 Years
ALL
No
Sponsors
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University Hospital, Tours
OTHER
Responsible Party
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Locations
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Chu Tours
Tours, , France
Countries
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Other Identifiers
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RIPH3-RNI18-Elastogreffe
Identifier Type: -
Identifier Source: org_study_id
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