Multiparametric MRI for Assessment of Changes of Renal Hemodynamics After Fistula Closure in Kidney Transplant Patients

NCT ID: NCT05015231

Last Updated: 2021-08-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-01

Study Completion Date

2027-12-31

Brief Summary

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Assessment of changes of renal hemodynamics by multiparametric MRI after closure of AVF access.

Detailed Description

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Conditions

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Kidney Transplantation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Echocardiography and MRI

Echocardiography and renal MRI before and after fistula closure

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Written informed consent
* Age \> 18 years
* Patients wishing to close the fistula and planned for surgical fistula closure
* eGFR CKD EPI ≥ 45 ml/min/1.73m2 at one year post transplantation
* Stable eGFR within the past 6 months
* Controlled blood pressure

Exclusion Criteria

* Kidney Transplantation \< 12 months before fistula closure
* Proteinuria \> 500mg/d
* Presence of donor specific antibodies
* Rejection within the past 6 months
* BK virus replication within the past 3 months
* Cardiac pacemaker, which is not compatible with MRI
* Claustrophobia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thomas Müller, Professor

Role: PRINCIPAL_INVESTIGATOR

University Hospital Zurich, Nephrology

Locations

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University Hospital Zurich

Zurich, , Switzerland

Site Status RECRUITING

Countries

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Switzerland

Central Contacts

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Thomas Müller, Professor

Role: CONTACT

0041 (0)44 255 11 11

Facility Contacts

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Thomas Müller, Professor

Role: primary

0041 (0)44 255 11 11

Other Identifiers

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2021-00474

Identifier Type: -

Identifier Source: org_study_id

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