Changes in Elastic Properties of Descending Thoracic Aorta After Ascending Aorta Replacement

NCT ID: NCT03817008

Last Updated: 2019-01-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

19 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-01

Study Completion Date

2019-01-17

Brief Summary

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The aim of our study was to evaluate the impact of aortic root replacement by a graft on the elastic properties of the descending thoracic aorta using cardiac Magnetic Resonance Imaging (MRI) and automatic post-processing.

Nineteen patients were operated on an aortic root aneurysm and a cardiac MRI allowing aortic compliance measurement was performed before and after surgery. Images were acquired with a 1.5 T MRI with only one additional sequence to a conventional aortic MRI protocol.

Detailed Description

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Observational and retrospective trial on medical data only. The patients are operated of planned aortic root aneurysm without additional intervention.

The pre and postoperative cardiac MRI are planned in standard of care.

Conditions

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Aortic Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Ascending aorta replacement with graft

Patient with planned Ascending aorta replacement with graft

Intervention Type PROCEDURE

Other Intervention Names

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cardiac MRI

Eligibility Criteria

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Inclusion Criteria

* \> 18 years
* Elective patient
* Ascending aorta replacement with graft

Exclusion Criteria

* Prior cardiac surgery
* Contraindication to performing cardiac MRI
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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JAZAYERI Aline

UNKNOWN

Sponsor Role collaborator

BOUCHOT Olivier

UNKNOWN

Sponsor Role collaborator

JAZAYERI Saed

UNKNOWN

Sponsor Role collaborator

MALAPERT Ghislain

UNKNOWN

Sponsor Role collaborator

PETROSYAN Andreanik

UNKNOWN

Sponsor Role collaborator

Centre Hospitalier La Chartreuse

OTHER

Sponsor Role lead

Responsible Party

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MORGANT Marie-Catherine

PI

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Morgant MC, Miteran J, Lin S, Laubriet A, Cochet A, Lalande A, Bouchot O. Impact of ascending aorta replacement by graft on elastic properties of descending thoracic aorta evaluated by cardiac magnetic resonance imaging. MAGMA. 2020 Oct;33(5):641-647. doi: 10.1007/s10334-020-00829-5. Epub 2020 Jan 31.

Reference Type DERIVED
PMID: 32006121 (View on PubMed)

Other Identifiers

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MORGANT 2019

Identifier Type: -

Identifier Source: org_study_id

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