Impact of Grafts and Endografts for Abdominal Aneurysms on Arterial Stiffness.
NCT ID: NCT02642952
Last Updated: 2019-01-30
Study Results
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View full resultsBasic Information
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COMPLETED
52 participants
OBSERVATIONAL
2016-01-31
2017-02-28
Brief Summary
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Our main goal is to measure the changes in:
Augmentation index, central blood pressure, pulse wave analysis, pulse wave velocity.
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Detailed Description
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We will use the device called: SphygmocoR (Atcor Medical, Sydney, Australia).
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Open-graft group
Patients treated for abdominal aortic aneurysm with open graft will be measured for central hemodynamics and arterial stiffness by non-invasive methods.
non-invasive methods
To measure central hemodynamics and arterial stiffness by non-invasive methods using SphygmocoR (Atcor Medical, Sydney, Australia) before and after the procedure.
Endograft group
Patients treated for abdominal aortic aneurysm with endograft will be measured for central hemodynamics and arterial stiffness by non-invasive methods.
non-invasive methods
To measure central hemodynamics and arterial stiffness by non-invasive methods using SphygmocoR (Atcor Medical, Sydney, Australia) before and after the procedure.
Interventions
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non-invasive methods
To measure central hemodynamics and arterial stiffness by non-invasive methods using SphygmocoR (Atcor Medical, Sydney, Australia) before and after the procedure.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients who don´t want to sign the informed consent.
50 Years
90 Years
ALL
No
Sponsors
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Hospital Universitario Ramon y Cajal
OTHER
Responsible Party
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Andrés Reyes Valdivia
Vascular Surgery Consultant. MD, FEBVS
Principal Investigators
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Andrés Reyes, Consultant
Role: PRINCIPAL_INVESTIGATOR
Hospital Universitario Ramon y Cajal
Locations
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Vascular Surgery Department
Madrid, , Spain
Countries
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References
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Paraskevas KI, Bessias N, Psathas C, Akridas K, Dragios T, Nikitas G, Andrikopoulos V, Mikhailidis DP, Kyriakides ZS. Evaluation of aortic stiffness (aortic pulse-wave velocity) before and after elective abdominal aortic aneurysm repair procedures: a pilot study. Open Cardiovasc Med J. 2009 Dec 9;3:173-5. doi: 10.2174/1874192400903010173.
Kadoglou NP, Moulakakis KG, Papadakis I, Ikonomidis I, Alepaki M, Lekakis J, Liapis CD. Changes in aortic pulse wave velocity of patients undergoing endovascular repair of abdominal aortic aneurysms. J Endovasc Ther. 2012 Oct;19(5):661-6. doi: 10.1583/JEVT-12-3916MR.1.
Kadoglou NP, Moulakakis KG, Papadakis I, Ikonomidis I, Alepaki M, Spathis A, Karakitsos P, Lekakis J, Liapis CD. Differential effects of stent-graft fabrics on arterial stiffness in patients undergoing endovascular aneurysm repair. J Endovasc Ther. 2014 Dec;21(6):850-8. doi: 10.1583/14-4772MR.1.
Lantelme P, Dzudie A, Milon H, Bricca G, Legedz L, Chevalier JM, Feugier P. Effect of abdominal aortic grafts on aortic stiffness and central hemodynamics. J Hypertens. 2009 Jun;27(6):1268-76. doi: 10.1097/HJH.0b013e3283299b22.
Valdivia AR, Fuente MF, Santos AD, Urena MG, Lozano AR, Guaita JO, Zuniga CG, Donas K, Ruiz JS. Impact of the Aortic Graft on Arterial Stiffness and Inflammatory Biomarkers after Endovascular Aortic Repair or Open Surgical Repair in Abdominal Aortic Aneurysm Disease. Ann Vasc Surg. 2019 Aug;59:84-90. doi: 10.1016/j.avsg.2018.12.092. Epub 2019 Feb 23.
Other Identifiers
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IMPACT001
Identifier Type: -
Identifier Source: org_study_id
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