Performance and Safety of a Second Generation Antimicrobial Graft in Abdominal Position

NCT ID: NCT01710878

Last Updated: 2013-11-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-02-29

Study Completion Date

2012-12-31

Brief Summary

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Safety and performance of an anti-microbial vascular graft in the treatment of aneurysmal and occlusive disease of the abdominal aorta.

Detailed Description

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The purpose of this multi center, single arm study is to demonstrate the safety and performance of the Second Generation Anti-Microbial (InterGard Synergy) vascular graft in the treatment of aneurismal and occlusive diseases of the abdominal aorta.

The primary endpoint is the assessment of primary and secondary graft patency. The secondary endpoints were the assessment of adverse events and the assessment of triclosan and silver contents in the serum over the time.

Conditions

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Abdominal Aorta Aneurysm

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intergard Synergy Graft

Group Type OTHER

Intergard Synergy Graft

Intervention Type DEVICE

Interventions

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Intergard Synergy Graft

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Patient aged 18-85 years

Patient presenting with an aorto-iliac occlusion (obstruction of flow) or stenosis, or aorto-iliac aneurysm and eligible for a revascularization with a bifurcated graft

Exclusion Criteria

Patient treated as an emergency

Patient included in another investigation

Patient pregnant or lactating or woman of childbearing potential

Patient with a known allergy to the material device used (collagen, triclosan, silver)

Patient with previous aorto-iliac bypass or replacement
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Maquet Cardiovascular

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Baptiste Ricco, MD

Role: PRINCIPAL_INVESTIGATOR

CHU La Milétrie

Locations

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CHRU

Angers, , France

Site Status

CHU Jean Minjoz

Besançon, , France

Site Status

CHU Dupuytren

Limoges, , France

Site Status

Hôpital Edouard Herriot

Lyon, , France

Site Status

Hôpital G. et R. Laennec

Nantes, , France

Site Status

Hôpital Pompidou

Paris, , France

Site Status

CHU La Milétrie

Poitiers, , France

Site Status

Krankenhaus Nordwest

Frankfurt, , Germany

Site Status

Countries

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France Germany

Other Identifiers

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HR07-001

Identifier Type: -

Identifier Source: org_study_id