Aortic Elongation and Dissection

NCT ID: NCT02722889

Last Updated: 2017-03-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

298 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-03-31

Study Completion Date

2017-01-31

Brief Summary

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Aim of this study is to measure length of the ascending aorta in adults and to investigate the clinical implication of 'elongation' of the aorta.

Detailed Description

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Regarding to aortic geometry, attention is often drawn to aortic diameters since an increase in these diameters (e.g. aneurysm) can lead to life-threatening complications such as dissection and/or rupture. In daily practice however (e.g. imaging reports), the investigators often encounter patients with elongation of the ascending aorta. Little is known about the length of the proximal aorta. Furthermore, the clinical implications of an elongated aorta are unknown.

Conditions

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Thoracic Aorta

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Healthy controls

Healthy control patients

No interventions assigned to this group

Type A dissection

Patients with proven type A dissection,

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Underwent recent (\<6 years) contrast-enhanced CT scan which allows for segmentation and assessment of aortic geometry.

Exclusion Criteria

* Age \<18 years old.
* Prior thoracic, cardiac or aortic surgery.
* Genetic disease with cardiac and/or aortic involvement (e.g. Marfan's disease).
* Infectious disease of the aorta.
* Malignant disease with involvement of heart and/or aorta.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joachim Wildberger, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Head of department of Radiology

Locations

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Maastricht University Medical Center

Maastricht, Limburg, Netherlands

Site Status

Countries

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Netherlands

Other Identifiers

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16-4-027

Identifier Type: -

Identifier Source: org_study_id

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