Venous Distension in Patients With Aneurysmatic Arterial Disease

NCT ID: NCT02867501

Last Updated: 2017-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

98 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-05-31

Study Completion Date

2017-03-28

Brief Summary

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The aim of the study is to assess if venous distension in patients with aneurysmatic arteriopathy is higher compared to patients with peripheral arterial occlusive disease (PAOD) and in controls.

Detailed Description

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Patients with aortic aneurysm and patients with PAOD and Controls will be investigated in the following manner: Duplexsonography with assessment of the arterial diameters in the aorta and leg arteries. Duplexsonography with assessment of venous reflux in proximal and deep veins of both legs Duplexsonography testing of venous distension in the common femoral vein, the great saphenous vein and the femoral vein.

Conditions

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Aortic Aneurysm, Abdominal Popliteal Artery Aneurysm Peripheral Arterial Occlusive Disease Vascular Diseases Aortic Diseases Varicose Veins

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Aneurysmatic disease

Patients with dilatative arteriopathy (DA) the aortic diameter must be \> 3 cm or the popliteal artery diameter \> 1.5 cm

No interventions assigned to this group

Peripheral arterial occlusive disease

Patients with arterial occlusive disease (PAOD) defined with an Ankle brachial index (ABI) \< 0.9 and positive criteria in the Edinburgh questionnaire.

No interventions assigned to this group

Healthy

Control group of age matched persons without PAOD (ABI \> 0.9) and without DA.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with dilatative arteriopathy (DA) the aortic diameter must be \> 3 cm or the popliteal artery diameter \> 1.5 cm
* Patients with arterial occlusive disease (PAOD) defined with an Ankle brachial index (ABI) \< 0.9 and positive criteria in the Edinburgh questionnaire
* Patients able to give informed consent
* Control group of age matched persons without PAOD (ABI \> 0.9) and without DA

Exclusion Criteria

* Impossibility to stand
* Diabetes
* No given informed consent
* Persons and patients \< 18 years old
* Acute deep venous thrombosis
* History of deep venous thrombosis
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kantonsspital Baselland Bruderholz

OTHER

Sponsor Role lead

Responsible Party

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Janis Christian Bartelt

intern

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Jeanneret C, Baldi T, Hailemariam S, Koella C, Gewaltig J, Biedermann BC. Selective loss of extracellular matrix proteins is linked to biophysical properties of varicose veins assessed by ultrasonography. Br J Surg. 2007 Apr;94(4):449-56. doi: 10.1002/bjs.5630.

Reference Type BACKGROUND
PMID: 17262753 (View on PubMed)

Jeanneret C, Jager KA, Zaugg CE, Hoffmann U. Venous reflux and venous distensibility in varicose and healthy veins. Eur J Vasc Endovasc Surg. 2007 Aug;34(2):236-42. doi: 10.1016/j.ejvs.2007.03.018. Epub 2007 May 24.

Reference Type BACKGROUND
PMID: 17524680 (View on PubMed)

Other Identifiers

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2016-00375

Identifier Type: -

Identifier Source: org_study_id

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